Shiming Chen

Affiliations: 
Ophthalmology Washington University School of Medicine, St. Louis, MO, United States 
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"Shiming Chen"
Mean distance: 18.46 (cluster 31)
 
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Publications

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Zheng Y, Chen S. (2024) Transcriptional precision in photoreceptor development and diseases - Lessons from 25 years of CRX research. Frontiers in Cellular Neuroscience. 18: 1347436
Shepherdson JL, Friedman RZ, Zheng Y, et al. (2024) Pathogenic variants in CRX have distinct -regulatory effects on enhancers and silencers in photoreceptors. Genome Research
Chen R, Li J, Wang J, et al. (2023) Integrated multi-omics single cell atlas of the human retina. Research Square
Wang J, Cheng X, Liang Q, et al. (2023) Single-cell multiomics of the human retina reveals hierarchical transcription factor collaboration in mediating cell type-specific effects of genetic variants on gene regulation. Genome Biology. 24: 269
Zheng Y, Sun C, Zhang X, et al. (2023) Missense mutations in CRX homeodomain cause dominant retinopathies through two distinct mechanisms. Elife. 12
Sun C, Ruzycki PA, Chen S. (2023) Rho enhancers play unexpectedly minor roles in Rhodopsin transcription and rod cell integrity. Scientific Reports. 13: 12899
Sun C, Chen S. (2023) Gene Augmentation for Autosomal Dominant CRX-Associated Retinopathies. Advances in Experimental Medicine and Biology. 1415: 135-141
Occelli LM, Tran NM, Chen S, et al. (2023) Cat LCA-CRX Model, Homozygous for an Antimorphic Mutation Has a Unique Phenotype. Translational Vision Science & Technology. 12: 15
Shepherdson JL, Friedman RZ, Zheng Y, et al. (2023) Pathogenic variants in CRX have distinct -regulatory effects on enhancers and silencers in photoreceptors. Biorxiv : the Preprint Server For Biology
Sun C, Chen S. (2023) Disease-causing mutations in genes encoding transcription factors critical for photoreceptor development. Frontiers in Molecular Neuroscience. 16: 1134839
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