Shobha Thangada

Affiliations: 
Cell Biology Univ of Connecticut Health Center, Farmington, CT, United States 
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"Shobha Thangada"
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Ghosh M, Thangada S, Dasgupta O, et al. (2018) Cell-intrinsic sphingosine kinase 2 promotes macrophage polarization and renal inflammation in response to unilateral ureteral obstruction. Plos One. 13: e0194053
Thangada S, Shapiro LH, Silva C, et al. (2014) Treatment with the immunomodulator FTY720 (fingolimod) significantly reduces renal inflammation in murine unilateral ureteral obstruction. The Journal of Urology. 191: 1508-16
Thangada S, Hla T, Grundy P, et al. (2012) 150 CONNECTIVE TISSUE GROWTH FACTOR (CTGF) AND SPHINGOSINE-1-PHOSPHATE (S1P) RECEPTOR 1 AND 2 LEVELS ARE ALTERED IN WILM'S TUMOR Journal of Urology. 187
Oo ML, Chang SH, Thangada S, et al. (2011) Engagement of S1P₁-degradative mechanisms leads to vascular leak in mice. The Journal of Clinical Investigation. 121: 2290-300
Skoura A, Michaud J, Im DS, et al. (2011) Sphingosine-1-phosphate receptor-2 function in myeloid cells regulates vascular inflammation and atherosclerosis. Arteriosclerosis, Thrombosis, and Vascular Biology. 31: 81-5
Thangada S, Khanna KM, Blaho VA, et al. (2010) Cell-surface residence of sphingosine 1-phosphate receptor 1 on lymphocytes determines lymphocyte egress kinetics. The Journal of Experimental Medicine. 207: 1475-83
Venkataraman K, Lee YM, Michaud J, et al. (2008) Vascular endothelium as a contributor of plasma sphingosine 1-phosphate. Circulation Research. 102: 669-76
Oo ML, Thangada S, Wu MT, et al. (2007) Immunosuppressive and anti-angiogenic sphingosine 1-phosphate receptor-1 agonists induce ubiquitinylation and proteasomal degradation of the receptor. The Journal of Biological Chemistry. 282: 9082-9
Venkataraman K, Thangada S, Michaud J, et al. (2006) Extracellular export of sphingosine kinase-1a contributes to the vascular S1P gradient. The Biochemical Journal. 397: 461-71
Jo E, Sanna MG, Gonzalez-Cabrera PJ, et al. (2005) S1P1-selective in vivo-active agonists from high-throughput screening: off-the-shelf chemical probes of receptor interactions, signaling, and fate. Chemistry & Biology. 12: 703-15
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