Igor E. Brodsky, Ph.D.

Affiliations: 
Stanford University, Palo Alto, CA 
Area:
Bacterial pathogenicity
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"Igor Brodsky"

Parents

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Stanley Falkow grad student 2004 Stanford
 (Role of Salmonella virulence genes in bacterial resistance to antimicrobial peptides and systemic disease.)
Ruslan Medzhitov post-doc (Chemistry Tree)
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Publications

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Matsuda R, Sorobetea D, Zhang J, et al. (2024) A TNF-IL-1 circuit controls Yersinia within intestinal pyogranulomas. The Journal of Experimental Medicine. 221
Wertman RS, Go CK, Saller BS, et al. (2023) Sequentially activated death complexes regulate pyroptosis and IL-1β release in response to blockade of immune signaling. Biorxiv : the Preprint Server For Biology
Herrmann BI, Grayczyk JP, Brodsky IE. (2023) Collab or Cancel? Bacterial Influencers of Inflammasome Signaling. Annual Review of Microbiology. 77: 451-477
Zhang J, Brodsky IE, Shin S. (2023) deploys type III-secreted effectors to evade caspase-4 inflammasome activation in human cells. Mbio. e0131023
Egan MS, O'Rourke EA, Mageswaran SK, et al. (2023) Inflammasomes primarily restrict cytosolic replication within human macrophages. Biorxiv : the Preprint Server For Biology
Pollock TY, Vázquez Marrero VR, Brodsky IE, et al. (2023) TNF licenses macrophages to undergo rapid caspase-1, -11, and -8-mediated cell death that restricts Legionella pneumophila infection. Plos Pathogens. 19: e1010767
Matsuda R, Sorobetea D, Zhang J, et al. (2023) A TNF-IL-1 circuit controls within intestinal granulomas. Biorxiv : the Preprint Server For Biology
Sorobetea D, Matsuda R, Peterson ST, et al. (2023) Inflammatory monocytes promote granuloma control of Yersinia infection. Nature Microbiology. 8: 666-678
Zhang J, Brodsky IE, Shin S. (2023) Type III-Secreted Effectors Subvert Caspase-4-dependent Inflammasome Activation in Human Cells. Biorxiv : the Preprint Server For Biology
Chen KW, Brodsky IE. (2022) Yersinia interactions with regulated cell death pathways. Current Opinion in Microbiology. 71: 102256
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