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Nathan J. Moerke, Ph.D.

Institution:
Harvard University, Cambridge, MA, United States
Area:
structural aspects of protein function
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"Nathan Moerke"
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Gerhard Wagner grad student 2006 Harvard
 (Structural and chemical genetic studies of eukaryotic translation initiation factors.)

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Publications

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Moerke N, Fallahi-Sichani M. (2016) Reverse Phase Protein Arrays for Compound Profiling. Current Protocols in Chemical Biology. 8: 179-196
Wei S, Kozono S, Kats L, et al. (2015) Active Pin1 is a key target of all-trans retinoic acid in acute promyelocytic leukemia and breast cancer. Nature Medicine. 21: 457-66
Fallahi-Sichani M, Moerke NJ, Niepel M, et al. (2015) Systematic analysis of BRAF(V600E) melanomas reveals a role for JNK/c-Jun pathway in adaptive resistance to drug-induced apoptosis. Molecular Systems Biology. 11: 797
Beauchemin C, Moerke NJ, Faloon P, et al. (2014) Assay Development and High-Throughput Screening for Inhibitors of Kaposi's Sarcoma-Associated Herpesvirus N-Terminal Latency-Associated Nuclear Antigen Binding to Nucleosomes. Journal of Biomolecular Screening. 19: 947-958
Tang Y, Xie T, Florian S, et al. (2013) Differential determinants of cancer cell insensitivity to antimitotic drugs discriminated by a one-step cell imaging assay. Journal of Biomolecular Screening. 18: 1062-71
Fallahi-Sichani M, Moerke NJ, Dastur A, et al. (2013) Abstract 5213: A systems biology approach to understanding differential phenotypic outcome of BRAF(V600E) inhibition in melanoma cells. Cancer Research. 73: 5213-5213
Moerke NJ, Hoffman GR. (2011) Development of in-cell Western assays using far-red fluorophores. Current Protocols in Chemical Biology. 3: 39-52
Hoeffer CA, Cowansage KK, Arnold EC, et al. (2011) Inhibition of the interactions between eukaryotic initiation factors 4E and 4G impairs long-term associative memory consolidation but not reconsolidation. Proceedings of the National Academy of Sciences of the United States of America. 108: 3383-8
Hoffman GR, Moerke NJ, Hsia M, et al. (2010) A high-throughput, cell-based screening method for siRNA and small molecule inhibitors of mTORC1 signaling using the In Cell Western technique. Assay and Drug Development Technologies. 8: 186-99
Moerke NJ. (2009) Fluorescence Polarization (FP) Assays for Monitoring Peptide-Protein or Nucleic Acid-Protein Binding. Current Protocols in Chemical Biology. 1: 1-15
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