Elizaveta Freinkman, Ph.D.

Affiliations: 
2012 Chemical Biology Harvard University, Cambridge, MA, United States 
Area:
molecular mechanisms of various antibiotics
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"Elizaveta Freinkman"
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Daniel E. Kahne grad student 2012 Harvard
 (Assembly and Regulation of the Lipopolysaccharide Transporter.)
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Publications

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Luengo A, Abbott KL, Davidson SM, et al. (2019) Reactive metabolite production is a targetable liability of glycolytic metabolism in lung cancer. Nature Communications. 10: 5604
Goldman A, Khiste S, Freinkman E, et al. (2019) Targeting tumor phenotypic plasticity and metabolic remodeling in adaptive cross-drug tolerance. Science Signaling. 12
Li H, Ericsson M, Rabasha B, et al. (2019) 6-Phosphogluconate Dehydrogenase Links Cytosolic Carbohydrate Metabolism to Protein Secretion via Modulation of Glutathione Levels. Cell Chemical Biology
Garcia-Bermudez J, Baudrier L, Bayraktar EC, et al. (2019) Squalene accumulation in cholesterol auxotrophic lymphomas prevents oxidative cell death. Nature
Petrova B, Liu K, Tian C, et al. (2018) Dynamic redox balance directs the oocyte-to-embryo transition via developmentally controlled reactive cysteine changes. Proceedings of the National Academy of Sciences of the United States of America
Kanarek N, Keys HR, Cantor JR, et al. (2018) Histidine catabolism is a major determinant of methotrexate sensitivity. Nature
Huang NJ, Lin YC, Lin CY, et al. (2018) Enhanced phosphocholine metabolism is essential for terminal erythropoiesis. Blood
Xu H, Lee MS, Tsai PY, et al. (2018) Ablation of insulin receptor substrates 1 and 2 suppresses-driven lung tumorigenesis. Proceedings of the National Academy of Sciences of the United States of America
McKenney AS, Lau AN, Somasundara AVH, et al. (2018) JAK2/IDH-mutant-driven myeloproliferative neoplasm is sensitive to combined targeted inhibition. The Journal of Clinical Investigation
Abu-Remaileh M, Wyant GA, Kim C, et al. (2017) Lysosomal metabolomics reveals V-ATPase and mTOR-dependent regulation of amino acid efflux from lysosomes. Science (New York, N.Y.)
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