Kathleen M. Sakamoto, Ph.D.
Affiliations: | 2004 | California Institute of Technology, Pasadena, CA |
Area:
Ubiquitin-Dependent Proteolysis and Cell DivisionGoogle:
"Kathleen Sakamoto"Parents
Sign in to add mentor| Raymond J. Deshaies | grad student | 2004 | Caltech | |
| (Targeting proteins for ubiquitination and degradation in the treatment of human disease.) | ||||
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Publications
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| Wilkes MC, Siva K, Varetti G, et al. (2020) Metformin-induced suppression of NLK improves erythropoiesis in pre-clinical models of Diamond Blackfan Anemia through induction of miR-26a. Experimental Hematology |
| Chae HD, Dutta R, Tiu B, et al. (2020) RSK inhibitor BI-D1870 inhibits acute myeloid leukemia cell proliferation by targeting mitotic exit. Oncotarget. 11: 2387-2403 |
| Wilkes MC, Siva K, Chen J, et al. (2020) Diamond Blackfan anemia is mediated by hyperactive Nemo-like kinase. Nature Communications. 11: 3344 |
| Wojcicki AV, Kasowski MM, Sakamoto KM, et al. (2020) Metabolomics in acute myeloid leukemia. Molecular Genetics and Metabolism |
| Huang M, Zeki J, Sumarsono N, et al. (2020) EPIGENETIC TARGETING OF TERT-ASSOCIATED GENE EXPRESSION SIGNATURE IN HUMAN NEUROBLASTOMA WITH TERT OVEREXPRESSION. Cancer Research |
| Youn M, Huang H, Chen C, et al. (2019) MMP9 inhibition increases erythropoiesis in RPS14-deficient del(5q) MDS models through suppression of TGF-β pathways. Blood Advances. 3: 2751-2763 |
| Chae HD, Cox N, Capolicchio S, et al. (2019) SAR optimization studies on modified salicylamides as a potential treatment for acute myeloid leukemia through inhibition of the CREB pathway. Bioorganic & Medicinal Chemistry Letters |
| Wilkes MC, Mercado JD, Saxena M, et al. (2019) Pharmacological Inhibition of Nemo-like Kinase Rescues mTOR-Mediated Translation and Primes Progenitors for Leucine-Stimulated Erythroid Expansion in Pre-Clinical Models of Diamond Blackfan Anemia Blood. 134: 455-455 |
| Wilkes M, Mercado J, Saxena M, et al. (2019) 3182 – PHARMACOLOGICAL INHIBITION OF NEMO-LIKE KINASE RESCUES MTOR-MEDIATED TRANSLATION AND ERYTHROPOIESIS IN PRE-CLINICAL MODELS OF DIAMOND BLACKFAN ANEMIA Experimental Hematology. 76: e5-e6 |
| Duque-Afonso J, Lin CH, Han K, et al. (2018) CBP modulates sensitivity to dasatinib in pre-BCR+ acute lymphoblastic leukemia. Cancer Research |