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Gregory S. Ducker, Ph.D.

Affiliations: 
2013 Chemistry University of California, Berkeley, Berkeley, CA, United States 
Area:
signal transduction pathways in cells and whole organisms
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"Gregory Ducker"
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Parents

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Joseph Walter Chihade research assistant 2004-2006 Carleton College
Kevan Michael Shokat grad student 2008-2013 UC Berkeley
 (Primary resistance to ATP-competitive mTOR inhibitors for the treatment of solid tumors.)
Joshua D. Rabinowitz post-doc 2013- Princeton

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Publications

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McBride MJ, Hunter CJ, Zhang Z, et al. (2024) Glycine homeostasis requires reverse SHMT flux. Cell Metabolism. 36: 103-115.e4
Dekhne AS, Shah K, Ducker GS, et al. (2023) Correction: Novel Pyrrolo[3,2-d]Pyrimidine Compounds Target Mitochondrial and Cytosolic One-Carbon Metabolism with Broad-spectrum Antitumor Efficacy. Molecular Cancer Therapeutics. OF1
Panic V, Pearson S, Banks J, et al. (2020) Mitochondrial pyruvate carrier is required for optimal brown fat thermogenesis. Elife. 9
García-Cañaveras JC, Lancho O, Ducker GS, et al. (2020) SHMT inhibition is effective and synergizes with methotrexate in T-cell acute lymphoblastic leukemia. Leukemia
Li AM, Ducker GS, Li Y, et al. (2020) Metabolic Profiling Reveals a Dependency of Human Metastatic Breast Cancer on Mitochondrial Serine and One-Carbon Unit Metabolism. Molecular Cancer Research : McR
Li AM, Ducker GS, Li Y, et al. (2020) Abstract 5713: Reprogramming of serine metabolism during breast cancer progression Cancer Research. 80: 5713-5713
Kuramoto J, Smith R, Kalasekar SM, et al. (2020) Abstract 3740: Role of phosphatidylcholine in β-catenin-driven hepatocellular carcinoma Cancer Research. 80: 3740-3740
Bensard CL, Wisidigama DR, Olson KA, et al. (2019) Regulation of Tumor Initiation by the Mitochondrial Pyruvate Carrier. Cell Metabolism
Dekhne AS, Shah K, Ducker GS, et al. (2019) Novel pyrrolo[3,2-d]pyrimidine compounds target mitochondrial and cytosolic one-carbon metabolism with broad-spectrum antitumor efficacy. Molecular Cancer Therapeutics
Rodriguez AE, Ducker GS, Billingham LK, et al. (2019) Serine Metabolism Supports Macrophage IL-1β Production. Cell Metabolism
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