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William T. Arthur, Ph.D.

Affiliations: 
2002 University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
Cytoskeleton, Focal Adhesions
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"William Arthur"
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Keith Burridge grad student 2002 UNC Chapel Hill
 (Regulation of RhoA by integrin -mediated adhesion.)

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Publications

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Madan B, Walker MP, Young R, et al. (2016) USP6 oncogene promotes Wnt signaling by deubiquitylating Frizzleds. Proceedings of the National Academy of Sciences of the United States of America
Conrad W, Major MB, Cleary MA, et al. (2013) FAM129B is a novel regulator of Wnt/β-catenin signal transduction in melanoma cells. F1000research. 2: 134
James RG, Biechele TL, Conrad WH, et al. (2009) Bruton's tyrosine kinase revealed as a negative regulator of Wnt-beta-catenin signaling. Science Signaling. 2: ra25
Dubash AD, Wennerberg K, García-Mata R, et al. (2007) A novel role for Lsc/p115 RhoGEF and LARG in regulating RhoA activity downstream of adhesion to fibronectin. Journal of Cell Science. 120: 3989-98
García-Mata R, Wennerberg K, Arthur WT, et al. (2006) Analysis of activated GAPs and GEFs in cell lysates. Methods in Enzymology. 406: 425-37
Arthur WT, Quilliam LA, Cooper JA. (2004) Rap1 promotes cell spreading by localizing Rac guanine nucleotide exchange factors. The Journal of Cell Biology. 167: 111-22
Avalos AM, Arthur WT, Schneider P, et al. (2004) Aggregation of integrins and RhoA activation are required for Thy-1-induced morphological changes in astrocytes. The Journal of Biological Chemistry. 279: 39139-45
Ellerbroek SM, Wennerberg K, Arthur WT, et al. (2004) SGEF, a RhoG guanine nucleotide exchange factor that stimulates macropinocytosis. Molecular Biology of the Cell. 15: 3309-19
Ballif BA, Arnaud L, Arthur WT, et al. (2004) Activation of a Dab1/CrkL/C3G/Rap1 pathway in Reelin-stimulated neurons. Current Biology : Cb. 14: 606-10
Wennerberg K, Forget MA, Ellerbroek SM, et al. (2003) Rnd proteins function as RhoA antagonists by activating p190 RhoGAP. Current Biology : Cb. 13: 1106-15
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