Diego Acosta-Alvear, Ph.D.

Affiliations: 
2008 Basic Medical Science New York University, New York, NY, United States 
Area:
Mammalian Transcription
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"Diego Acosta-Alvear"
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Brian David Dynlacht grad student 2008 NYU
 (Transcriptional control of the mammalian Unfolded Protein Response: Roles of XBP1 in non-secretory and secretory cells.)
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Publications

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Chowdhury SP, Solley SC, Polishchuk E, et al. (2024) Baseline Unfolded Protein Response Signaling Adjusts the Timing of the Mammalian Cell Cycle. Molecular Biology of the Cell. mbcE23110419
Dufey E, Bravo-San Pedro JM, Eggers C, et al. (2020) Genotoxic stress triggers the activation of IRE1α-dependent RNA decay to modulate the DNA damage response. Nature Communications. 11: 2401
Solley S, Zappa F, Acosta-Alvear D. (2020) Regulation of the mammalian cell cycle by the unfolded protein response The Faseb Journal. 34: 1-1
Karagöz GE, Aragón T, Acosta-Alvear D. (2019) Recent advances in signal integration mechanisms in the unfolded protein response. F1000research. 8
Harnoss JM, Le Thomas A, Shemorry A, et al. (2019) Disruption of IRE1α through its kinase domain attenuates multiple myeloma. Proceedings of the National Academy of Sciences of the United States of America
Karagöz GE, Acosta-Alvear D, Walter P. (2019) The Unfolded Protein Response: Detecting and Responding to Fluctuations in the Protein-Folding Capacity of the Endoplasmic Reticulum. Cold Spring Harbor Perspectives in Biology
Acosta-Alvear D, Karagöz GE, Fröhlich F, et al. (2018) The unfolded protein response and endoplasmic reticulum protein targeting machineries converge on the stress sensor IRE1. Elife. 7
Acosta-Alvear D, Karagöz GE, Fröhlich F, et al. (2018) Author response: The unfolded protein response and endoplasmic reticulum protein targeting machineries converge on the stress sensor IRE1 Elife
Karagöz GE, Acosta-Alvear D, Nguyen HT, et al. (2017) An unfolded protein-induced conformational switch activates mammalian IRE1. Elife. 6
Tufanli O, Telkoparan Akillilar P, Acosta-Alvear D, et al. (2017) Targeting IRE1 with small molecules counteracts progression of atherosclerosis. Proceedings of the National Academy of Sciences of the United States of America
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