Christopher G. Hubert, Ph.D.

Affiliations: 
2012 Molecular and Cellular Biology University of Washington, Seattle, Seattle, WA 
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James M. Olson grad student 2012 University of Washington
 (Identification of Cancer-Specific Essential Genes in Glioblastoma Multiforme.)
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Song X, Tiek D, Miki S, et al. (2024) RNA splicing analysis deciphers developmental hierarchies and reveals therapeutic targets in adult glioma. The Journal of Clinical Investigation
Verduin M, Hoosemans L, Vanmechelen M, et al. (2023) Patient-derived glioblastoma organoids reflect tumor heterogeneity and treatment sensitivity. Neuro-Oncology Advances. 5: vdad152
Hubert CG, Stauffer SR, Lathia JD. (2023) A TOX-ic axis of epigenetic stem cell maintenance and chemoresistance in colon cancer. Plos Biology. 21: e3002295
Mitchell K, Sprowls SA, Arora S, et al. (2023) WDR5 represents a therapeutically exploitable target for cancer stem cells in glioblastoma. Genes & Development
Sundar SJ, Shakya S, Recinos V, et al. (2022) Maintaining Human Glioblastoma Cellular Diversity Ex vivo using Three-Dimensional Organoid Culture. Journal of Visualized Experiments : Jove
Shields JA, Meier SR, Bandi M, et al. (2022) VRK1 is a Synthetic Lethal Target in VRK2-deficient Glioblastoma. Cancer Research
Hubert CG, Rich JN. (2022) Patient-derived explants as tumor models. Cancer Cell. 40: 348-350
Knudsen AM, Halle B, Cédile O, et al. (2021) Surgical resection of glioblastomas induces pleiotrophin-mediated self-renewal of glioblastoma stem cells in recurrent tumors. Neuro-Oncology
Sundar SJ, Shakya S, Barnett A, et al. (2021) Three-dimensional organoid culture unveils resistance to clinical therapies in adult and pediatric glioblastoma. Translational Oncology. 15: 101251
Shakya S, Gromovsky AD, Hale JS, et al. (2021) Altered lipid metabolism marks glioblastoma stem and non-stem cells in separate tumor niches. Acta Neuropathologica Communications. 9: 101
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