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Rhine R. Shen, Ph.D.

Affiliations: 
2006 University of California, Los Angeles, Los Angeles, CA 
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"Rhine Shen"
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Michael Teitell grad student 2006 UCLA
 (TCL1-mediated mature B cell lymphomagenesis.)

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Publications

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Locke FL, Filosto S, Chou J, et al. (2024) Impact of tumor microenvironment on efficacy of anti-CD19 CAR T cell therapy or chemotherapy and transplant in large B cell lymphoma. Nature Medicine
Neelapu SS, Jacobson CA, Ghobadi A, et al. (2023) 5-Year Follow-Up Supports Curative Potential of Axicabtagene Ciloleucel in Refractory Large B-Cell Lymphoma (ZUMA-1). Blood
Foubert P, Srihari S, Le Textier L, et al. (2020) Gene expression profiling and TCR diversity of ATA188, a Pre-manufactured, Allogeneic Epstein-Barr Virus-targeted T-cell Immunotherapy for Patients with Multiple Sclerosis Cytotherapy. 22: S115
Shen RR, Pham CD, Wu MM, et al. (2019) Abstract 2310: Functional demonstration of CD19 chimeric antigen receptor (CAR) engineered Epstein-Barr virus (EBV) specific T cells: An off-the-shelf, allogeneic CAR T-cell immunotherapy platform Cancer Research. 79: 2310-2310
Luo LY, Kim E, Cheung HW, et al. (2015) The Tyrosine Kinase Adaptor Protein FRS2 Is Oncogenic and Amplified in High-Grade Serous Ovarian Cancer. Molecular Cancer Research : McR. 13: 502-9
Shen RR, Zhou AY, Kim E, et al. (2015) TRAF2 is an NF-κB-activating oncogene in epithelial cancers. Oncogene. 34: 209-16
Zhu Z, Aref AR, Cohoon TJ, et al. (2014) Inhibition of KRAS-driven tumorigenicity by interruption of an autocrine cytokine circuit. Cancer Discovery. 4: 452-65
Hagerstrand D, Tong A, Schumacher SE, et al. (2013) Systematic interrogation of 3q26 identifies TLOC1 and SKIL as cancer drivers. Cancer Discovery. 3: 1044-57
Zhou AY, Shen RR, Kim E, et al. (2013) IKKε-mediated tumorigenesis requires K63-linked polyubiquitination by a cIAP1/cIAP2/TRAF2 E3 ubiquitin ligase complex. Cell Reports. 3: 724-33
Shen RR, Zhou AY, Kim E, et al. (2012) IκB kinase ε phosphorylates TRAF2 to promote mammary epithelial cell transformation. Molecular and Cellular Biology. 32: 4756-68
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