Daniel J. Murphy, Ph.D.

Affiliations: 
2000 University of Virginia, Charlottesville, VA 
Area:
Microbiology
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"Daniel Murphy"

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Daniel A. Engel grad student 2000 UVA
 (The human SWI -SNF component BRG1 inhibits transcription of the c-fos gene.)
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Publications

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Whyte D, Skalka G, Walsh P, et al. (2023) NUAK1 governs centrosome replication in pancreatic cancer via MYPT1/PP1β and GSK3β-dependent regulation of PLK4. Molecular Oncology
Rodrigues FS, Miranda VS, Carneiro-Lobo TC, et al. (2020) IKKβ Kinase Promotes Stemness, Migration, and Invasion in KRAS-Driven Lung Adenocarcinoma Cells. International Journal of Molecular Sciences. 21
Muthalagu N, Monteverde T, Raffo-Iraolagoitia X, et al. (2020) Repression of the Type I Interferon pathway underlies MYC & KRAS-dependent evasion of NK & B cells in Pancreatic Ductal Adenocarcinoma. Cancer Discovery
Yun S, Vincelette ND, Fernandez M, et al. (2020) Tfeb Links MYC Signaling to Epigenetic Control of Acute Myeloid Leukemia Cell Death and Differentiation Blood. 136: 12-13
Bott AJ, Shen J, Tonelli C, et al. (2019) Glutamine Anabolism Plays a Critical Role in Pancreatic Cancer by Coupling Carbon and Nitrogen Metabolism. Cell Reports. 29: 1287-1298.e6
Neidler S, Kruspig B, Hewit K, et al. (2019) Identification of a Clinically Relevant Signature for Early Progression in KRAS-Driven Lung Adenocarcinoma. Cancers. 11
Kruspig B, Monteverde T, Neidler S, et al. (2018) The ERBB network facilitates KRAS-driven lung tumorigenesis. Science Translational Medicine. 10
Port JLF, Muthalagu N, Raja M, et al. (2018) Colorectal tumors require NUAK1 for protection from oxidative stress. Cancer Discovery
Walton JB, Farquharson M, Mason S, et al. (2017) CRISPR/Cas9-derived models of ovarian high grade serous carcinoma targeting Brca1, Pten and Nf1, and correlation with platinum sensitivity. Scientific Reports. 7: 16827
Farrell AS, Joly MM, Allen-Petersen BL, et al. (2017) MYC regulates ductal-neuroendocrine lineage plasticity in pancreatic ductal adenocarcinoma associated with poor outcome and chemoresistance. Nature Communications. 8: 1728
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