Frank G. Bottone, Ph.D.
Affiliations: | 2005 | North Carolina State University, Raleigh, NC |
Area:
Nutrition, Molecular BiologyGoogle:
"Frank Bottone"Parents
Sign in to add mentor| Brenda Alston-Mills | grad student | 2005 | NCSU | |
| (The biology and regulation of activating transcription factor 3 (ATF3) by nonsteroidal anti-inflammatory drugs (NSAIDs) and dietary compounds with chemopreventive activity.) | ||||
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| Bottone FG, Alston-Mills B. (2011) The dietary compounds resveratrol and genistein induce activating transcription factor 3 while suppressing inhibitor of DNA binding/differentiation-1. Journal of Medicinal Food. 14: 584-93 |
| Lee CR, Bottone FG, Krahn JM, et al. (2007) Identification and functional characterization of polymorphisms in human cyclooxygenase-1 (PTGS1). Pharmacogenetics and Genomics. 17: 145-60 |
| Moon Y, Bottone FG, McEntee MF, et al. (2005) Suppression of tumor cell invasion by cyclooxygenase inhibitors is mediated by thrombospondin-1 via the early growth response gene Egr-1. Molecular Cancer Therapeutics. 4: 1551-8 |
| Kim JS, Baek SJ, Bottone FG, et al. (2005) Overexpression of 15-lipoxygenase-1 induces growth arrest through phosphorylation of p53 in human colorectal cancer cells. Molecular Cancer Research : McR. 3: 511-7 |
| Bottone FG, Moon Y, Alston-Mills B, et al. (2005) Transcriptional regulation of activating transcription factor 3 involves the early growth response-1 gene. The Journal of Pharmacology and Experimental Therapeutics. 315: 668-77 |
| Bottone FG, Moon Y, Kim JS, et al. (2005) The anti-invasive activity of cyclooxygenase inhibitors is regulated by the transcription factor ATF3 (activating transcription factor 3). Molecular Cancer Therapeutics. 4: 693-703 |
| Ishibashi M, Bottone FG, Taniura S, et al. (2005) The cyclooxygenase inhibitor indomethacin modulates gene expression and represses the extracellular matrix protein laminin gamma1 in human glioblastoma cells. Experimental Cell Research. 302: 244-52 |
| Nixon JB, Kim KS, Lamb PW, et al. (2004) 15-Lipoxygenase-1 has anti-tumorigenic effects in colorectal cancer. Prostaglandins, Leukotrienes, and Essential Fatty Acids. 70: 7-15 |
| Bottone FG, Martinez JM, Alston-Mills B, et al. (2004) Gene modulation by Cox-1 and Cox-2 specific inhibitors in human colorectal carcinoma cancer cells. Carcinogenesis. 25: 349-57 |
| Bottone FG, Martinez JM, Collins JB, et al. (2003) Gene modulation by the cyclooxygenase inhibitor, sulindac sulfide, in human colorectal carcinoma cells: possible link to apoptosis. The Journal of Biological Chemistry. 278: 25790-801 |