Yahao Bu, Ph.D.

Affiliations: 
2007 Roswell Park - Cellular and Molecular Biology State University of New York, Buffalo, Buffalo, NY, United States 
Area:
Cell Biology
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"Yahao Bu"

Parents

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Irwin H. Gelman grad student 2007 SUNY Buffalo
 (Dissection of the SSeCKS metastasis suppressor gene promoters: Identification of v -Src responsive elements.)
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Publications

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Cutler MJ, Belko KE, Bu Y, et al. (2019) Abstract 4717: Effective preclinical management of angiosarcoma with oral paclitaxel Cancer Research. 79: 4717-4717
Smolinski MP, Bu Y, Clements J, et al. (2018) Discovery of Novel Dual Mechanism of Action Src Signaling and Tubulin Polymerization Inhibitors (KX2-391 and KX2-361). Journal of Medicinal Chemistry
Gao Z, Bu Y, Liu X, et al. (2016) TCDD promoted EMT of hFPECs via AhR, which involved the activation of EGFR/ERK signaling. Toxicology and Applied Pharmacology
Anbalagan M, Ali A, Jones RK, et al. (2012) Peptidomimetic Src/pretubulin inhibitor KX-01 alone and in combination with paclitaxel suppresses growth, metastasis in human ER/PR/HER2-negative tumor xenografts. Molecular Cancer Therapeutics. 11: 1936-47
Fallah-Tafti A, Foroumadi A, Tiwari R, et al. (2011) Thiazolyl N-benzyl-substituted acetamide derivatives: synthesis, Src kinase inhibitory and anticancer activities. European Journal of Medicinal Chemistry. 46: 4853-8
Bu Y, Gao L, Gelman IH. (2011) Role for transcription factor TFII-I in the suppression of SSeCKS/Gravin/Akap12 transcription by Src. International Journal of Cancer. Journal International Du Cancer. 128: 1836-42
Su B, Bu Y, Engelberg D, et al. (2010) SSeCKS/Gravin/AKAP12 inhibits cancer cell invasiveness and chemotaxis by suppressing a protein kinase C- Raf/MEK/ERK pathway. The Journal of Biological Chemistry. 285: 4578-86
Bu Y, Gao L, Hangauer D, et al. (2010) Abstract 2534: Suppression of prostate cancer growth by the Src signaling inhibitor, KXO1 (KX2-391) Cancer Research. 70: 2534-2534
Bu Y, Smolinski M, Qu J, et al. (2010) Abstract 2487: Mechanism of action KX01 (KX2-391), a novel tubulin polymerization and Src signaling inhibitor proceeding to Phase II clinical trials Cancer Research. 70: 2487-2487
Sachdev S, Bu Y, Gelman IH. (2009) Paxillin-Y118 phosphorylation contributes to the control of Src-induced anchorage-independent growth by FAK and adhesion. Bmc Cancer. 9: 12
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