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E Premkumar Reddy

Affiliations: 
Molecular Biology and Genetics Temple University, Philadelphia, PA, United States 
Area:
Molecular Biology
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"E Reddy"
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Children

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Atul Kumar grad student 2001 Temple University
Anita L. Korapati grad student 2002 Temple University
Quang D. Nguyen grad student 2003 Temple University
Rachel B. Sumerson grad student 2003 Temple University
James K. Mangan grad student 2005 Temple University
Yen K. Lieu grad student 2006 Temple University
Zahidur R. Abedin grad student 2008 Temple University
Rachna Chawla grad student 2008 Temple University
Haritha K. DLReddy grad student 2008 Temple University
James J. Yi grad student 2008 Temple University
Amol A. Padgaonkar grad student 2014 Temple University

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Publications

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Sato K, Padgaonkar A, Cosenza S, et al. (2020) Abstract P5-05-04: A novel inhibitor of cancer stem cells overcomes chemotherapy resistance of triple negative breast cancers Cancer Research
Padgaonkar A, Rechkoblit O, Vasquez-Del Carpio R, et al. (2018) Targeting protein kinase CK2 and CDK4/6 pathways with a multi-kinase inhibitor ON108110 suppresses pro-survival signaling and growth in mantle cell lymphoma and T-acute lymphoblastic leukemia. Oncotarget. 9: 37753-37765
Perumal D, Kuo PY, Leshchenko VV, et al. (2016) Dual Targeting of CDK4 and ARK5 Using a Novel Kinase Inhibitor ON123300 Exerts Potent Anticancer Activity against Multiple Myeloma. Cancer Research
Reddy MV, Akula B, Jatiani S, et al. (2015) Discovery of 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one (7ao) as a potent selective inhibitor of Polo like kinase 2 (PLK2). Bioorganic & Medicinal Chemistry
Eachkoti R, Reddy MV, Lieu YK, et al. (2014) Identification and characterisation of a novel heat shock protein 90 inhibitor ONO4140. European Journal of Cancer (Oxford, England : 1990). 50: 1982-92
Baker SJ, Ma'ayan A, Lieu YK, et al. (2014) B-myb is an essential regulator of hematopoietic stem cell and myeloid progenitor cell development. Proceedings of the National Academy of Sciences of the United States of America. 111: 3122-7
Reddy MV, Akula B, Cosenza SC, et al. (2014) Discovery of 8-cyclopentyl-2-[4-(4-methyl-piperazin-1-yl)-phenylamino]-7-oxo-7,8-dihydro-pyrido[2,3-d]pyrimidine-6-carbonitrile (7x) as a potent inhibitor of cyclin-dependent kinase 4 (CDK4) and AMPK-related kinase 5 (ARK5). Journal of Medicinal Chemistry. 57: 578-99
Perumal D, Leshchenko VV, Kuo P, et al. (2014) Weighted Gene Co-Expression Network Analysis (WGCNA) Identifies Highly Proliferative Myeloma Subgroup Responsive to CDK4/ARK5 Inhibition Blood. 124: 3445-3445
Reddy MV, Mallireddigari MR, Pallela VR, et al. (2013) Design, synthesis, and biological evaluation of (E)-N-aryl-2-arylethenesulfonamide analogues as potent and orally bioavailable microtubule-targeted anticancer agents. Journal of Medicinal Chemistry. 56: 5562-86
Baker SJ, Reddy EP. (2012) CDK4: A Key Player in the Cell Cycle, Development, and Cancer. Genes & Cancer. 3: 658-69
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