Robert L. Kortum, Ph.D.
Affiliations: | 2004 | University of Nebraska Medical Center, Omaha, NE, United States |
Area:
Molecular Biology, Cell BiologyGoogle:
"Robert Kortum"Parents
Sign in to add mentor| Robert E. Lewis | grad student | 2004 | University of Nebraska Medical Center | |
| (The molecular scaffold KSR1 regulates proliferative, oncogenic, and adipogenic potential.) | ||||
BETA: Related publications
See more...
Publications
|
You can help our author matching system! If you notice any publications incorrectly attributed to this author, please sign in and mark matches as correct or incorrect. |
| Theard PL, Linke AJ, Sealover NE, et al. (2023) SOS2 modulates the threshold of EGFR signaling to regulate osimertinib efficacy and resistance in lung adenocarcinoma. Molecular Oncology |
| Daley BR, Vieira HM, Rao C, et al. (2023) SOS1 and KSR1 modulate MEK inhibitor responsiveness to target resistant cell populations based on PI3K and KRAS mutation status. Proceedings of the National Academy of Sciences of the United States of America. 120: e2313137120 |
| Theard PL, Linke AJ, Sealover NE, et al. (2023) SOS2 regulates the threshold of mutant -dependent oncogenesis. Biorxiv : the Preprint Server For Biology |
| Hebron KE, Wan X, Roth JS, et al. (2022) The combination of trametinib and ganitumab is effective in RAS-mutated PAX-fusion negative rhabdomyosarcoma models. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research |
| Sheffels E, Kortum RL. (2021) Breaking Oncogene Addiction: Getting RTK/RAS-Mutated Cancers off the SOS. Journal of Medicinal Chemistry |
| Sheffels E, Kortum RL. (2021) The Role of Wild-Type RAS in Oncogenic RAS Transformation. Genes. 12 |
| Theard PL, Sheffels E, Sealover NE, et al. (2020) Marked synergy by vertical inhibition of EGFR signaling in NSCLC spheroids shows SOS1 is a therapeutic target in EGFR-mutated cancer. Elife. 9 |
| Terrell EM, Durrant DE, Ritt DA, et al. (2019) Distinct Binding Preferences between Ras and Raf Family Members and the Impact on Oncogenic Ras Signaling. Molecular Cell |
| Sheffels E, Sealover NE, Theard PL, et al. (2019) Anchorage-independent growth conditions reveal a differential SOS2 dependence for transformation and survival in RAS-mutant cancer cells. Small Gtpases. 1-12 |
| Sheffels E, Sealover NE, Wang C, et al. (2018) Oncogenic RAS isoforms show a hierarchical requirement for the guanine nucleotide exchange factor SOS2 to mediate cell transformation. Science Signaling. 11 |