Christina M. Mundy, Ph.D.

Affiliations: 
2014 Cell Biology Temple University, Philadelphia, PA, United States 
Area:
Cell Biology, Immunology, Physiology Biology
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"Christina Mundy"

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Steven N. Popoff grad student 2014 Temple University
 (The interaction between connective tissue growth factor and bone morphogenetic protein-2 during osteoblast differentiation and function.)
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Publications

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Yao L, Lu J, Zhong L, et al. (2023) Activin A marks a novel progenitor cell population during fracture healing and reveals a therapeutic strategy. Elife. 12
Billings PC, Bizzaro C, Yang E, et al. (2020) Human and mouse activin genes: Divergent expression of activin A protein variants and identification of a novel heparan sulfate-binding domain in activin B. Plos One. 15: e0229254
Mundy C, Yang E, Takano H, et al. (2018) Heparan sulfate antagonism alters bone morphogenetic protein signaling and receptor dynamics, suggesting a mechanism in Hereditary Multiple Exostoses. The Journal of Biological Chemistry
Sinha S, Mundy C, Bechtold T, et al. (2017) Unsuspected osteochondroma-like outgrowths in the cranial base of Hereditary Multiple Exostoses patients and modeling and treatment with a BMP antagonist in mice. Plos Genetics. 13: e1006742
Mundy C, Bello A, Sgariglia F, et al. (2016) HhAntag, a Hedgehog Signaling Antagonist, Suppresses Chondrogenesis and Modulates Canonical and Non-Canonical BMP Signaling. Journal of Cellular Physiology. 231: 1033-44
Bechtold TE, Saunders C, Mundy C, et al. (2015) Excess BMP Signaling in Heterotopic Cartilage Forming in Prg4-null TMJ Discs. Journal of Dental Research
Lambi AG, Tarr JT, Hindin DI, et al. (2015) Abstract 83 Plastic and Reconstructive Surgery. 135: 63
Mundy C, Gannon M, Popoff SN. (2014) Connective tissue growth factor (CTGF/CCN2) negatively regulates BMP-2 induced osteoblast differentiation and signaling. Journal of Cellular Physiology. 229: 672-81
Huegel J, Mundy C, Sgariglia F, et al. (2013) Perichondrium phenotype and border function are regulated by Ext1 and heparan sulfate in developing long bones: a mechanism likely deranged in Hereditary Multiple Exostoses. Developmental Biology. 377: 100-12
Lambi AG, Pankratz TL, Mundy C, et al. (2012) The skeletal site-specific role of connective tissue growth factor in prenatal osteogenesis. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 241: 1944-59
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