Jeffrey A. Engelman, Ph.D.
Affiliations: | 2000 | Yeshiva University, New York, NY, United States |
Area:
Molecular Biology, PharmacologyGoogle:
"Jeffrey Engelman"Mean distance: 6635.5
Parents
Sign in to add mentor| Michael P. Lisanti | grad student | 2000 | Yeshiva University | |
| (The roles of caveolin-1 and MAP kinase pathways in cellular transformation and differentiation.) | ||||
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Publications
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| Crowe MS, Zavorotinskaya T, Voliva CF, et al. (2021) RAF-mutant melanomas differentially depend on ERK2 over ERK1 to support aberrant MAPK pathway activation and cell proliferation. Molecular Cancer Research : McR |
| Chakrabarty A, Rexer BN, Wang SE, et al. (2010) H1047R phosphatidylinositol 3-kinase mutant enhances HER2-mediated transformation by heregulin production and activation of HER3 Oncogene. 29: 5193-5203 |
| Razani B, Wang XB, Engelman JA, et al. (2002) Caveolin-2-deficient mice show evidence of severe pulmonary dysfunction without disruption of caveolae. Molecular and Cellular Biology. 22: 2329-44 |
| Razani B, Engelman JA, Wang XB, et al. (2001) Caveolin-1 null mice are viable but show evidence of hyperproliferative and vascular abnormalities. The Journal of Biological Chemistry. 276: 38121-38 |
| Lee H, Woodman SE, Engelman JA, et al. (2001) Palmitoylation of caveolin-1 at a single site (Cys-156) controls its coupling to the c-Src tyrosine kinase: targeting of dually acylated molecules (GPI-linked, transmembrane, or cytoplasmic) to caveolae effectively uncouples c-Src and caveolin-1 (TYR-14). The Journal of Biological Chemistry. 276: 35150-8 |
| Galbiati F, Engelman JA, Volonte D, et al. (2001) Caveolin-3 null mice show a loss of caveolae, changes in the microdomain distribution of the dystrophin-glycoprotein complex, and t-tubule abnormalities. The Journal of Biological Chemistry. 276: 21425-33 |
| Engelman JA, Berg AH, Lewis RY, et al. (2000) Tumor necrosis factor alpha-mediated insulin resistance, but not dedifferentiation, is abrogated by MEK1/2 inhibitors in 3T3-L1 adipocytes. Molecular Endocrinology (Baltimore, Md.). 14: 1557-69 |
| Engelman JA, Berg AH, Lewis RY, et al. (1999) Constitutively active mitogen-activated protein kinase kinase 6 (MKK6) or salicylate induces spontaneous 3T3-L1 adipogenesis. The Journal of Biological Chemistry. 274: 35630-8 |
| Engelman JA, Zhang XL, Razani B, et al. (1999) p42/44 MAP kinase-dependent and -independent signaling pathways regulate caveolin-1 gene expression. Activation of Ras-MAP kinase and protein kinase a signaling cascades transcriptionally down-regulates caveolin-1 promoter activity. The Journal of Biological Chemistry. 274: 32333-41 |
| Smart EJ, Graf GA, McNiven MA, et al. (1999) Caveolins, liquid-ordered domains, and signal transduction. Molecular and Cellular Biology. 19: 7289-304 |