Celina M. D'Cruz, Ph.D.
Affiliations: | 2000 | University of Pennsylvania, Philadelphia, PA, United States |
Area:
Molecular Biology, OncologyGoogle:
"Celina D'Cruz"Parents
Sign in to add mentor| Lewis A. Chodosh | grad student | 2000 | Penn | |
| (Analysis of parity-induced protection against breast cancer.) | ||||
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Publications
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| Ladd B, Mazzola AM, Bihani T, et al. (2016) Effective combination therapies in preclinical endocrine resistant breast cancer models harboring ER mutations. Oncotarget |
| Weir HM, Bradbury RH, Lawson M, et al. (2016) AZD9496: An oral estrogen receptor inhibitor that blocks the growth of ER-positive and ESR1 mutant breast tumours in preclinical models. Cancer Research |
| Davies B, Guan N, Logie A, et al. (2015) Tumors with AKT1E17K mutations are rational targets for single agent or combination therapy with AKT inhibitors. Molecular Cancer Therapeutics |
| Bihani T, Ezell SA, Ladd B, et al. (2015) Resistance to everolimus driven by epigenetic regulation of MYC in ER+ breast cancers. Oncotarget. 6: 2407-20 |
| Liu Z, Wang M, Alvarez JV, et al. (2008) Singular value decomposition-based regression identifies activation of endogenous signaling pathways in vivo. Genome Biology. 9: R180 |
| Cowling VH, D'Cruz CM, Chodosh LA, et al. (2007) c-Myc transforms human mammary epithelial cells through repression of the Wnt inhibitors DKK1 and SFRP1. Molecular and Cellular Biology. 27: 5135-46 |
| Blakely CM, Stoddard AJ, Belka GK, et al. (2006) Hormone-induced protection against mammary tumorigenesis is conserved in multiple rat strains and identifies a core gene expression signature induced by pregnancy. Cancer Research. 66: 6421-31 |
| Blakely CM, Sintasath L, D'Cruz CM, et al. (2005) Developmental stage determines the effects of MYC in the mammary epithelium. Development (Cambridge, England). 132: 1147-60 |
| D'Cruz CM, Moody SE, Master SR, et al. (2002) Persistent parity-induced changes in growth factors, TGF-beta3, and differentiation in the rodent mammary gland. Molecular Endocrinology (Baltimore, Md.). 16: 2034-51 |
| Master SR, Hartman JL, D'Cruz CM, et al. (2002) Functional microarray analysis of mammary organogenesis reveals a developmental role in adaptive thermogenesis. Molecular Endocrinology (Baltimore, Md.). 16: 1185-203 |