Douglas B. Stairs, Ph.D.
Affiliations: | 2004 | University of Pennsylvania, Philadelphia, PA, United States |
Area:
Molecular Biology, Cell Biology, GeneticsGoogle:
"Douglas Stairs"Parents
Sign in to add mentor| Lewis A. Chodosh | grad student | 2004 | Penn | |
| (Discovery, characterization and functional analysis of the serine /threonine kinase Krct.) | ||||
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Publications
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| Chalmers FE, Mogre S, Rimal B, et al. (2022) The unfolded protein response gene Ire1α is required for tissue renewal and normal differentiation in the mouse tongue and esophagus. Developmental Biology. 492: 59-70 |
| Chalmers FE, Stairs DB, Glick AB. (2020) Abstract 5839: The unfolded protein response gene Ire1α is required for tissue renewal and normal differentiation in the mouse tongue and esophagus Cancer Research. 80: 5839-5839 |
| Lehman HL, Kidacki M, Warrick JI, et al. (2018) NFkB hyperactivation causes invasion of esophageal squamous cell carcinoma with EGFR overexpression and p120-catenin down-regulation. Oncotarget. 9: 11180-11196 |
| Kidacki M, Lehman HL, Green MV, et al. (2017) p120-Catenin Downregulation and PIK3CA Mutations Cooperate to Induce Invasion through MMP1 in HNSCC. Molecular Cancer Research : McR |
| Karagoz K, Lehman HL, Stairs DB, et al. (2016) Proteomic and Metabolic Signatures of Esophageal Squamous Cell Carcinoma. Current Cancer Drug Targets |
| Lehman HL, Yang X, Welsh PA, et al. (2015) p120-catenin down-regulation and epidermal growth factor receptor overexpression results in a transformed epithelium that mimics esophageal squamous cell carcinoma. The American Journal of Pathology. 185: 240-51 |
| Vega ME, Giroux V, Natsuizaka M, et al. (2014) Inhibition of Notch signaling enhances transdifferentiation of the esophageal squamous epithelium towards a Barrett's-like metaplasia via KLF4. Cell Cycle (Georgetown, Tex.). 13: 3857-66 |
| Chen CC, Stairs DB, Boxer RB, et al. (2012) Autocrine prolactin induced by the Pten-Akt pathway is required for lactation initiation and provides a direct link between the Akt and Stat5 pathways. Genes & Development. 26: 2154-68 |
| Kong J, Crissey MA, Stairs DB, et al. (2011) Cox2 and β-catenin/T-cell factor signaling intestinalize human esophageal keratinocytes when cultured under organotypic conditions. Neoplasia (New York, N.Y.). 13: 792-805 |
| Stairs DB, Bayne LJ, Rhoades B, et al. (2011) Deletion of p120-catenin results in a tumor microenvironment with inflammation and cancer that establishes it as a tumor suppressor gene. Cancer Cell. 19: 470-83 |