Shugaku Takeda, Ph.D.
Affiliations: | 2010 | Biology & Biomedical Sciences (Developmental Biology) | Washington University, Saint Louis, St. Louis, MO |
Area:
Human Development, Cell Biology, Molecular BiologyGoogle:
"Shugaku Takeda"Parents
Sign in to add mentor| James J. Hsieh | grad student | 2010 | Washington University | |
| (The roles of MLL and Taspase1-mediated MLL proteolysis in embryogenesis and the HGF-MET signaling pathway.) | ||||
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Publications
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| Niizuma H, Searleman AC, Takeda S, et al. (2021) Taspase1 orchestrates fetal liver hematopoietic stem cell and vertebrae fates through cleaving TFIIA. Jci Insight |
| Takeda S, Andreu-Agullo C, Sridhar S, et al. (2019) Abstract LB-277: Characterization of the anti-cancer and immunologic activity of RGX-019, a novel pre-clinical stage humanized monoclonal antibody targeting the MERTK receptor Cancer Research. 79 |
| Tavazoie MF, Pollack I, Tanqueco R, et al. (2018) LXR/ApoE Activation Restricts Innate Immune Suppression in Cancer. Cell |
| Kurth I, Andreu C, Takeda S, et al. (2018) Abstract 5863: RGX-202, a first-in-class small-molecule inhibitor of the creatine transporter SLC6a8, is a robust suppressor of cancer growth and metastatic progression Cancer Research. 78: 5863-5863 |
| Wang GX, Tu HC, Dong Y, et al. (2017) ΔNp63 Inhibits Oxidative Stress-Induced Cell Death, Including Ferroptosis, and Cooperates with the BCL-2 Family to Promote Clonogenic Survival. Cell Reports. 21: 2926-2939 |
| Nargund AM, Pham CG, Dong Y, et al. (2017) The SWI/SNF Protein PBRM1 Restrains VHL-Loss-Driven Clear Cell Renal Cell Carcinoma. Cell Reports. 18: 2893-2906 |
| Chen HC, Kanai M, Inoue-Yamauchi A, et al. (2015) An interconnected hierarchical model of cell death regulation by the BCL-2 family. Nature Cell Biology |
| Takeda S, Sasagawa S, Oyama T, et al. (2015) Taspase1-dependent TFIIA cleavage coordinates head morphogenesis by limiting Cdkn2a locus transcription. The Journal of Clinical Investigation. 125: 1203-14 |
| Voss MH, Hakimi AA, Pham CG, et al. (2014) Tumor genetic analyses of patients with metastatic renal cell carcinoma and extended benefit from mTOR inhibitor therapy. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 20: 1955-64 |
| Oyama T, Sasagawa S, Takeda S, et al. (2013) Cleavage of TFIIA by Taspase1 activates TRF2-specified mammalian male germ cell programs. Developmental Cell. 27: 188-200 |