Demetrios Kalaitzidis, Ph.D.

Affiliations: 
2006 Boston University, Boston, MA, United States 
Area:
Molecular Biology, Cell Biology
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"Demetrios Kalaitzidis"

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Thomas D. Gilmore grad student 2006 Boston University
 (Characterization of the mis-regulated REL/NF -kappaB pathway in the RC -K8 human lymphoma cell line and characterization of a conditionally active REL -estrogen receptor fusion protein.)
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Publications

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McEwan B, Kuppuraju M, Padalia Z, et al. (2020) Abstract 880: Allogeneic CAR-T cell products containing 10 gene edits using CRISPR/Cas9 can retain full functionality in vivo and in vitro Immunology. 80: 880-880
Padalia Z, Dunn A, Karagiannis K, et al. (2020) Abstract 879: Functional and single-cell assessment of CRISPR-modified CAR-T cells from NSCLC patients and healthy donors Immunology
McEwan B, Padalia Z, Porras A, et al. (2019) Abstract 1428: Allogeneic CRISPR/Cas9 gene-edited CAR-T cells targeting CD33 show potent preclinical activity against AML cells Cancer Research. 79: 1428-1428
Dar H, Henderson D, Padalia Z, et al. (2018) Preclinical Development of CTX120, an Allogeneic CAR-T Cell Targeting Bcma Blood. 132: 1921-1921
Padalia Z, Porras A, Dequeant ML, et al. (2018) Abstract 2551: Allogeneic CRISPR engineered anti CD70 CAR T cells demonstrate potent preclinical activity against both solid and hematological cancer cells Cancer Research. 78: 2551-2551
Lee PY, Sykes DB, Ameri S, et al. (2017) The metabolic regulator mTORC1 controls terminal myeloid differentiation. Science Immunology. 2
Kalaitzidis D, Lee D, Efeyan A, et al. (2017) Amino acid-insensitive mTORC1 regulation enables nutritional stress resilience in hematopoietic stem cells. The Journal of Clinical Investigation
Lee D, Wang YH, Kalaitzidis D, et al. (2016) Endogenous transmembrane protein UT2 inhibits pSTAT3 and suppresses hematological malignancy. The Journal of Clinical Investigation
Lee D, Sykes SM, Kalaitzidis D, et al. (2014) Transmembrane Inhibitor of RICTOR/mTORC2 in Hematopoietic Progenitors. Stem Cell Reports. 3: 832-40
Kalaitzidis D, Scadden DT. (2014) Deep diving in the blood stem cell-ome. The Embo Journal. 33: 2281-2
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