Michael R. Garbati, Ph.D.

Affiliations: 
2010 Boston University, Boston, MA, United States 
Area:
Molecular Biology
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"Michael Garbati"

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Thomas D. Gilmore grad student 2010 Boston University
 (Identification of IkappaB kinase phosphorylation sites on human transcription factor REL and characterization of histone acetyltransferase P300 as a REL coactivator.)
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Publications

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Lai HY, Brooks SA, Craver BM, et al. (2019) Defective negative regulation of Toll-like receptor signaling leads to excessive TNF-α in myeloproliferative neoplasm. Blood Advances. 3: 122-131
Garbati MR, Welgan CA, Landefeld SH, et al. (2015) Mutant calreticulin-expressing cells induce monocyte hyperreactivity through a paracrine mechanism. American Journal of Hematology
Garbati MR, Hays LE, Rathbun RK, et al. (2015) Cytokine overproduction and crosslinker hypersensitivity are unlinked in Fanconi anemia macrophages. Journal of Leukocyte Biology
Lai HY, Morse SJ, Nguyen TK, et al. (2015) A Blunted Response to the Anti-Inflammatory Cytokine IL-10 Contributes to Excessive TNF Production in Myeloproliferative Neoplasm Blood. 126: 1632-1632
Newell LF, Holtan SG, Rosenzweig J, et al. (2015) Placental Growth Factor Enhances Toll-like Receptor-Induced Inflammatory Cytokine Gene Expression Transcriptionally in Human Mononuclear Phagocytes Blood. 126: 1006-1006
Garbati M, Bagby GC. (2015) Deficiency of the c-JUN Inhibitor DACH1 in FA Macrophages Accounts for the Cytokine Overproduction Phenotype Blood. 126: 1002-1002
Garbati M, Keeble W, Yang W, et al. (2015) Alda-1 Constrains TLR-Induced Cytokine Overproduction By Fanconi Anemia Macrophages By Enhancing ALDH1A1 Activity Blood. 126: 1000-1000
Newell LF, Rathbun RK, Garbati MR, et al. (2014) The Contribution of Toll-like Receptor (TLR) Pathway Hyper-Reactivity to Clonal Selection in Secondary MDS and AML Blood. 124: 4621-4621
Garbati MR, Rathbun RK, Yates JE, et al. (2014) ALDH1A1 Dysfunction in FA-Deficient Macrophages Contributes to Aberrant Activation of the Innate Immune Response Blood. 124: 4107-4107
Garbati MR, Hays LE, Keeble W, et al. (2013) FANCA and FANCC modulate TLR and p38 MAPK-dependent expression of IL-1β in macrophages. Blood. 122: 3197-205
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