Ronald A. DePinho, MD
Affiliations: | President | University of Texas MD Anderson Cancer Center, Houston, TX, United States |
Area:
molecular and biological processes governing the development of cancer, the basis for aging and degenerative diseases, and the maintenance of normal and cancer stem cells.Website:
http://www.dfhcc.harvard.edu/membership/profile/member/107/0/Google:
"Ronald DePinho"Bio:
http://faculty.mdanderson.org/Ronald_DePinho/
Cross-listing: Neurotree - Chemistry Tree
Parents
Sign in to add mentor| Matthew D. Scharff | post-doc | 1984-1985 | Albert Einstein (ID Tree) |
| Frederick W. Alt | post-doc | 1984-1988 | Columbia (Neurotree) |
Children
Sign in to add trainee| Ken Scott | grad student | (FlyTree) | |
| Sandy Chang | post-doc | University of Texas | |
| Han-Woong Lee | post-doc | Sungkyunkwan University, Korea | |
| Steven E. Artandi | post-doc | 2000 | Dana-Farber Cancer Institute |
| Adam T Boutin | post-doc | 2008-2016 | Dana Farber Cancer Institute, Harvard Medical School (Neurotree) |
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Publications
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| Han J, Xu J, Liu Y, et al. (2023) Stromal-derived NRG1 enables oncogenic KRAS bypass in pancreas cancer. Genes & Development |
| Li J, Lan Z, Liao W, et al. (2023) Histone demethylase KDM5D upregulation drives sex differences in colon cancer. Nature |
| Lee R, Li J, Li J, et al. (2022) Synthetic Essentiality of Tryptophan 2,3-dioxygenase 2 in APC-Mutated Colorectal Cancer. Cancer Discovery |
| Dayde D, Gunther J, Hirayama Y, et al. (2021) Identification of Blood-Based Biomarkers for the Prediction of the Response to Neoadjuvant Chemoradiation in Rectal Cancer. Cancers. 13 |
| Zhao D, Cai L, Lu X, et al. (2020) Chromatin Regulator, CHD1, Remodels the Immunosuppressive Tumor Microenvironment in PTEN-Deficient Prostate Cancer. Cancer Discovery |
| Huang T, Cheng X, Chahoud J, et al. (2020) Effective combinatorial immunotherapy for penile squamous cell carcinoma. Nature Communications. 11: 2124 |
| Hou P, Kapoor A, Zhang Q, et al. (2020) Tumor microenvironment remodeling enables bypass of oncogenic KRAS dependency in pancreatic cancer. Cancer Discovery |
| Li X, Qian X, Wang B, et al. (2020) Programmable base editing of mutated TERT promoter inhibits brain tumour growth. Nature Cell Biology |
| Dey P, Li J, Zhang J, et al. (2020) Oncogenic Kras driven metabolic reprogramming in pancreas cancer cells utilizes cytokines from the tumor microenvironment. Cancer Discovery |
| Chen P, Hsu WH, Chang A, et al. (2020) Circadian regulator CLOCK recruits immune suppressive microglia into the GBM tumor microenvironment. Cancer Discovery |