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Kent L. Rossman, Ph.D.

Affiliations: 
2002 University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
Biochemistry
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"Kent Rossman"
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John E. Sondek grad student 2002 UNC Chapel Hill
 (Structural and biochemical characterization of Dbl -family proteins.)

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Publications

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Lawson CD, Fan C, Mitin N, et al. (2016) Rho GTPase Transcriptome Analysis Reveals Oncogenic Roles for Rho GTPase-activating Proteins in Basal-like Breast Cancers. Cancer Research
Hobbs GA, Der CJ, Rossman KL. (2016) RAS isoforms and mutations in cancer at a glance. Journal of Cell Science
Kim TY, Siesser PF, Rossman KL, et al. (2015) Substrate trapping proteomics reveals targets of the βTrCP2/FBXW11 ubiquitin ligase. Molecular and Cellular Biology. 35: 167-81
Damoulakis G, Gambardella L, Rossman KL, et al. (2014) P-Rex1 directly activates RhoG to regulate GPCR-driven Rac signalling and actin polarity in neutrophils. Journal of Cell Science. 127: 2589-600
Cook DR, Rossman KL, Der CJ. (2014) Rho guanine nucleotide exchange factors: regulators of Rho GTPase activity in development and disease. Oncogene. 33: 4021-35
Mitin N, Rossman KL, Currin R, et al. (2013) The RhoGEF TEM4 Regulates Endothelial Cell Migration by Suppressing Actomyosin Contractility. Plos One. 8: e66260
Mitin N, Rossman KL, Der CJ. (2012) Identification of a novel actin-binding domain within the Rho guanine nucleotide exchange factor TEM4. Plos One. 7: e41876
Neel NF, Rossman KL, Martin TD, et al. (2012) The RalB small GTPase mediates formation of invadopodia through a GTPase-activating protein-independent function of the RalBP1/RLIP76 effector. Molecular and Cellular Biology. 32: 1374-86
Justilien V, Jameison L, Der CJ, et al. (2011) Oncogenic activity of Ect2 is regulated through protein kinase C iota-mediated phosphorylation. The Journal of Biological Chemistry. 286: 8149-57
Vigil D, Cherfils J, Rossman KL, et al. (2010) Ras superfamily GEFs and GAPs: validated and tractable targets for cancer therapy? Nature Reviews. Cancer. 10: 842-57
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