Christopher N. Batuello, Ph.D.

Affiliations: 
2012 Biochemistry and Molecular Biology Indiana University, Bloomington, Bloomington, IN, United States 
Area:
Molecular Biology, Biochemistry, General Biology
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"Christopher Batuello"

Parents

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Lindsey D. Mayo grad student 2012 Indiana University
 (Phospho-regulation and metastatic potential of murine double minute 2.)
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Publications

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Hauck P, Wolf E, Olivos D, et al. (2017) Early Stage Metastasis require Mdm2 and not p53 Gain of Function. Molecular Cancer Research : McR
Tonsing-Carter E, Bailey BJ, Saadatzadeh MR, et al. (2015) Potentiation of carboplatin-mediated DNA damage by the Mdm2 modulator Nutlin-3a in a humanized orthotopic breast-to-lung metastatic model. Molecular Cancer Therapeutics
Batuello CN, Hauck PM, Gendron JM, et al. (2015) Src phosphorylation converts Mdm2 from a ubiquitinating to a neddylating E3 ligase. Proceedings of the National Academy of Sciences of the United States of America. 112: 1749-54
Lehman JA, Hauck PM, Gendron JM, et al. (2013) Serdemetan antagonizes the Mdm2-HIF1α axis leading to decreased levels of glycolytic enzymes. Plos One. 8: e74741
Lehman JA, Waning DL, Batuello CN, et al. (2011) Induction of apoptotic genes by a p73-phosphatase and tensin homolog (p73-PTEN) protein complex in response to genotoxic stress. The Journal of Biological Chemistry. 286: 36631-40
Waning DL, Lehman JA, Batuello CN, et al. (2011) c-Abl phosphorylation of Mdm2 facilitates Mdm2-Mdmx complex formation. The Journal of Biological Chemistry. 286: 216-22
Waning DL, Lehman JA, Batuello CN, et al. (2010) Controlling the Mdm2-Mdmx-p53 Circuit. Pharmaceuticals (Basel, Switzerland). 3: 1576-1593
Araki S, Eitel JA, Batuello CN, et al. (2010) TGF-beta1-induced expression of human Mdm2 correlates with late-stage metastatic breast cancer. The Journal of Clinical Investigation. 120: 290-302
Lehman JA, Eitel JA, Batuello CN, et al. (2008) Therapeutic considerations for Mdm2: not just a one trick pony. Expert Opinion On Drug Discovery. 3: 1309-1321
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