Anthony G. Clementz, Ph.D.

Affiliations: 
2010 Molecular and Cellular Biochemistry Program Loyola University Chicago, Chicago, IL, United States 
Area:
Biochemistry, Oncology
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"Anthony Clementz"

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Clodia Osipo grad student 2010 Loyola University Chicago
 (Polyomavirus enhancer activator 3 (PEA3), a member of the Ets family of transcription factors, is a transcriptional activator of Notch-1 and Notch-4 in breast cancer: An opportunity for novel combinational therapy.)
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Publications

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Rizzo P, Mele D, Caliceti C, et al. (2014) The role of notch in the cardiovascular system: potential adverse effects of investigational notch inhibitors. Frontiers in Oncology. 4: 384
Pandya K, Meeke K, Clementz AG, et al. (2011) Targeting both Notch and ErbB-2 signalling pathways is required for prevention of ErbB-2-positive breast tumour recurrence. British Journal of Cancer. 105: 796-806
Clementz AG, Rogowski A, Pandya K, et al. (2011) NOTCH-1 and NOTCH-4 are novel gene targets of PEA3 in breast cancer: novel therapeutic implications. Breast Cancer Research : Bcr. 13: R63
Pandya K, Meeke K, Rogowski A, et al. (2011) Abstract 2553: Inhibition of γ-secretase in combination with Lapatinib induces tumor regressionin vivo Cancer Research. 71: 2553-2553
Clementz AG, Rizzo P, Miele L, et al. (2010) Abstract 3918: PEA3 is a novel transcriptional activator of Notch-1 and Notch-4 in breast cancer: Opportunity for a new combination strategy Cancer Research. 70: 3918-3918
Clementz AG, Osipo C. (2009) Notch versus the proteasome: what is the target of gamma-secretase inhibitor-I? Breast Cancer Research : Bcr. 11: 110
Osipo C, Patel P, Rizzo P, et al. (2008) ErbB-2 inhibition activates Notch-1 and sensitizes breast cancer cells to a gamma-secretase inhibitor. Oncogene. 27: 5019-32
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