Brian M. Necela, Ph.D.

Affiliations: 
2000 Medical University of South Carolina, Charleston, SC, United States 
Area:
Molecular Biology, Pharmacology, Biochemistry
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"Brian Necela"
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Barry Ledford grad student 2000 MUSC
 (Expression of novel ARNT isoforms specifically affect AHR -dependent signaling pathways.)
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Publications

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Vasmatzis G, Wang X, Smadbeck JB, et al. (2018) Chromoanasynthesis is a common mechanism that leads to ERBB2 amplifications in a cohort of early stage HER2 breast cancer samples. Bmc Cancer. 18: 738
Norton N, Fox N, McCarl CA, et al. (2018) Generation of HER2-specific antibody immunity during trastuzumab adjuvant therapy associates with reduced relapse in resected HER2 breast cancer. Breast Cancer Research : Bcr. 20: 52
Serie DJ, Crook JE, Necela BM, et al. (2017) Breast Cancer Clinical Trial of Chemotherapy and Trastuzumab: Potential Tool to Identify Cardiac Modifying Variants of Dilated Cardiomyopathy. Journal of Cardiovascular Development and Disease. 4
Davila JI, Starr JS, Attia S, et al. (2017) Comprehensive Genomic Profiling of a Rare Thyroid Follicular Dendritic Cell Sarcoma. Rare Tumors. 9: 6834
Serie DJ, Crook JE, Necela BM, et al. (2017) Genome-wide association study of cardiotoxicity in the NCCTG N9831 (Alliance) adjuvant trastuzumab trial. Pharmacogenetics and Genomics
Necela BM, Axenfeld BC, Serie DJ, et al. (2017) The antineoplastic drug, trastuzumab, dysregulates metabolism in iPSC-derived cardiomyocytes. Clinical and Translational Medicine. 6: 5
Perez EA, Ballman KV, Mashadi-Hossein A, et al. (2017) Intrinsic Subtype and Therapeutic Response Among HER2-Positive Breaty st Tumors from the NCCTG (Alliance) N9831 Trial. Journal of the National Cancer Institute. 109
Chumsri S, Serie DJ, Necela BM, et al. (2017) Abstract 3377: Simultaneous analysis of the mutational landscape and RNA and protein expression profile of HER2-positive breast cancer using 3D BiologyTM Cancer Research. 77: 3377-3377
Holst F, Hoivik EA, Gibson WJ, et al. (2016) Recurrent hormone-binding domain truncated ESR1 amplifications in primary endometrial cancers suggest their implication in hormone independent growth. Scientific Reports. 6: 25521
Norton N, Advani PP, Serie DJ, et al. (2016) Assessment of Tumor Heterogeneity, as Evidenced by Gene Expression Profiles, Pathway Activation, and Gene Copy Number, in Patients with Multifocal Invasive Lobular Breast Tumors. Plos One. 11: e0153411
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