Matthew J. Giacalone, Ph.D.

Affiliations: 
2006 University of California, San Diego and San Diego State University 
Area:
Microbiology Biology, Cell Biology, Virology Biology
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"Matthew Giacalone"
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Kathleen L. McGuire grad student 2006 University of California, San Diego and San Diego State University
 (The use of bacterial minicells as a broad spectrum vaccine delivery vehicle.)
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Publications

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Grenier SF, Khan MW, Reil KA, et al. (2023) VAX014, an Oncolytic Therapy, Reduces Adenomas and Modifies Colon Microenvironment in Mouse Model of CRC. International Journal of Molecular Sciences. 24
Reil KA, Tsuji S, Molina E, et al. (2023) Intralesional administration of VAX014 facilitates in situ immunization and potentiates immune checkpoint blockade in immunologically cold tumors. Journal For Immunotherapy of Cancer. 11
Tsuji S, Reil K, Nelson K, et al. (2022) Intravesical VAX014 Synergizes with PD-L1 Blockade to Enhance Local and Systemic Control of Bladder Cancer. Cancer Immunology Research
Hancock BM, McGuire KL, Tsuji S, et al. (2016) A Single Intravesical Instillation of VAX014 Inhibits Orthotopic Superficial Bladder Tumor Implantation to Increase Survival. Anticancer Research. 36: 6243-6248
Tsuji S, Chen X, Hancock B, et al. (2016) Preclinical evaluation of VAX-IP, a novel bacterial minicell-based biopharmaceutical for nonmuscle invasive bladder cancer. Molecular Therapy Oncolytics. 3: 16004
Khan MW, Tsuji S, Tian M, et al. (2016) Abstract A05: Immunity, the colonic environment, and colon cancer Cancer Research. 76
Newman MJ, Benbatoul K, Hancock B, et al. (2012) Abstract 5703: Efficient targeted delivery of protein toxins using self-manufacturing nanoparticles (minicells) derived from bacteria Cancer Research. 72: 5703-5703
Giacalone MJ, Zapata JC, Berkley NL, et al. (2007) Immunization with non-replicating E. coli minicells delivering both protein antigen and DNA protects mice from lethal challenge with lymphocytic choriomeningitis virus. Vaccine. 25: 2279-87
Giacalone MJ, Sabbadini RA, Chambers AL, et al. (2007) Corrigendum to "Immune responses elicited by bacterial minicells capable of simultaneous DNA and protein antigen delivery" [Vaccine 2006;24(33-34):6009-6017] (DOI:10.1016/j.vaccine.2006.04.063) Vaccine. 25: 3515
Giacalone MJ, Gentile AM, Lovitt BT, et al. (2006) The use of bacterial minicells to transfer plasmid DNA to eukaryotic cells. Cellular Microbiology. 8: 1624-33
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