Anthony W. Partridge, Ph.D.
Affiliations: | 2004 | University of Toronto, Toronto, ON, Canada |
Area:
BiochemistryGoogle:
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Parents
Sign in to add mentorCharles Deber | grad student | 2004 | University of Toronto | |
(Aberrant transmembrane helix -helix interactions as a biophysical cause of human disease.) |
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Publications
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Kasper SH, Otten S, Squadroni B, et al. (2023) A high-throughput microfluidic mechanoporation platform to enable intracellular delivery of cyclic peptides in cell-based assays. Bioengineering & Translational Medicine. 8: e10542 |
Ng S, Brueckner AC, Bahmanjah S, et al. (2022) Discovery and Structure-Based Design of Macrocyclic Peptides Targeting STUB1. Journal of Medicinal Chemistry |
Garrigou M, Sauvagnat B, Duggal R, et al. (2022) Accelerated Identification of Cell Active KRAS Inhibitory Macrocyclic Peptides using Mixture Libraries and Automated Ligand Identification System (ALIS) Technology. Journal of Medicinal Chemistry. 65: 8961-8974 |
Li J, Kannan S, Aronica P, et al. (2022) Molecular descriptors suggest stapling as a strategy for optimizing membrane permeability of cyclic peptides. The Journal of Chemical Physics. 156: 065101 |
Sun Y, Lau SY, Lim ZW, et al. (2022) Phase-separating peptides for direct cytosolic delivery and redox-activated release of macromolecular therapeutics. Nature Chemistry. 14: 274-283 |
Lim S, Boyer N, Boo N, et al. (2021) Discovery of cell active macrocyclic peptides with on-target inhibition of KRAS signaling. Chemical Science. 12: 15975-15987 |
Desai TJ, Habulihaz B, Cannon JR, et al. (2021) Correction to: Liposome Click Membrane Permeability Assay for Identifying Permeable Peptides. Pharmaceutical Research |
Desai TJ, Habulihaz B, Cannon JR, et al. (2021) Liposome Click Membrane Permeability Assay for Identifying Permeable Peptides. Pharmaceutical Research |
Peier A, Ge L, Boyer N, et al. (2021) NanoClick: A High Throughput, Target-Agnostic Peptide Cell Permeability Assay. Acs Chemical Biology |
Ng S, Juang YC, Chandramohan A, et al. (2020) De-risking Drug Discovery of Intracellular Targeting Peptides: Screening Strategies to Eliminate False-Positive Hits. Acs Medicinal Chemistry Letters. 11: 1993-2001 |