Claudia S. Hofmann, Ph.D.

Affiliations: 
2003 Boston University, Boston, MA, United States 
Area:
Molecular Biology, Cell Biology, Nutrition
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Gail E. Sonenshein grad student 2003 Boston University
 (Control of vascular smooth muscle cell matrix synthesis and proliferation by B-myb and green tea polyphenol.)
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Publications

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Scharl M, Mwinyi J, Fischbeck A, et al. (2012) Crohn's disease-associated polymorphism within the PTPN2 gene affects muramyl-dipeptide-induced cytokine secretion and autophagy. Inflammatory Bowel Diseases. 18: 900-12
Gäbele E, Dostert K, Hofmann C, et al. (2011) DSS induced colitis increases portal LPS levels and enhances hepatic inflammation and fibrogenesis in experimental NASH. Journal of Hepatology. 55: 1391-9
Hausmann M, Leucht K, Ploner C, et al. (2011) BCL-2 modifying factor (BMF) is a central regulator of anoikis in human intestinal epithelial cells. The Journal of Biological Chemistry. 286: 26533-40
Hofmann C, Chen N, Obermeier F, et al. (2011) C1q/TNF-related protein-3 (CTRP-3) is secreted by visceral adipose tissue and exerts antiinflammatory and antifibrotic effects in primary human colonic fibroblasts. Inflammatory Bowel Diseases. 17: 2462-71
Hausmann M, Kellermeier S, Hofmann C, et al. (2008) 971 Knock Down of BMF Maintains Survival of Primary Intestinal Epithelial Cells Gastroenterology. 134
Hofmann C, Dunger N, Grunwald N, et al. (2008) 304 T-Cell-Dependent Protective Effects of CpG-ODN in Experimental Colitis Are Mediated By CD11c+ Dendritic Cells Gastroenterology. 134
Hofmann CS, Wang X, Sullivan CP, et al. (2005) B-Myb represses elastin gene expression in aortic smooth muscle cells. The Journal of Biological Chemistry. 280: 7694-701
Hofmann CS, Sullivan CP, Jiang HY, et al. (2004) B-Myb represses vascular smooth muscle cell collagen gene expression and inhibits neointima formation after arterial injury. Arteriosclerosis, Thrombosis, and Vascular Biology. 24: 1608-13
Hofmann CS, Sonenshein GE. (2003) Green tea polyphenol epigallocatechin-3 gallate induces apoptosis of proliferating vascular smooth muscle cells via activation of p53. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 17: 702-4
Yang W, Shen J, Wu M, et al. (2001) Repression of transcription of the p27(Kip1) cyclin-dependent kinase inhibitor gene by c-Myc. Oncogene. 20: 1688-702
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