Shangquin Guo, Ph.D.

Affiliations: 
2005 Boston University, Boston, MA, United States 
Area:
Molecular Biology
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"Shangquin Guo"
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Gail E. Sonenshein grad student 2005 Boston University
 (Molecular analysis of green tea polyphenol epigallocatechin -3 -gallate inhibition of Her -2 /neu signalling in breast cancer.)
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Publications

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Belguise K, Guo S, Yang S, et al. (2007) Green tea polyphenols reverse cooperation between c-Rel and CK2 that induces the aryl hydrocarbon receptor, slug, and an invasive phenotype. Cancer Research. 67: 11742-50
Belguise K, Guo S, Sonenshein GE. (2007) Activation of FOXO3a by the green tea polyphenol epigallocatechin-3-gallate induces estrogen receptor alpha expression reversing invasive phenotype of breast cancer cells. Cancer Research. 67: 5763-70
Guo S, Lu J, Subramanian A, et al. (2006) Microarray-assisted pathway analysis identifies mitogen-activated protein kinase signaling as a mediator of resistance to the green tea polyphenol epigallocatechin 3-gallate in her-2/neu-overexpressing breast cancer cells. Cancer Research. 66: 5322-9
Eddy SF, Guo S, Demicco EG, et al. (2005) Inducible IkappaB kinase/IkappaB kinase epsilon expression is induced by CK2 and promotes aberrant nuclear factor-kappaB activation in breast cancer cells. Cancer Research. 65: 11375-83
Guo S, Yang S, Taylor C, et al. (2005) Green tea polyphenol epigallocatechin-3 gallate (EGCG) affects gene expression of breast cancer cells transformed by the carcinogen 7,12-dimethylbenz[a]anthracene. The Journal of Nutrition. 135: 2978S-2986S
Guo S, Sonenshein GE. (2004) Forkhead box transcription factor FOXO3a regulates estrogen receptor alpha expression and is repressed by the Her-2/neu/phosphatidylinositol 3-kinase/Akt signaling pathway. Molecular and Cellular Biology. 24: 8681-90
Pianetti S, Guo S, Kavanagh KT, et al. (2002) Green tea polyphenol epigallocatechin-3 gallate inhibits Her-2/neu signaling, proliferation, and transformed phenotype of breast cancer cells. Cancer Research. 62: 652-5
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