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Alexander Mankin

Affiliations: 
University of Illinois at Chicago, Health Sciences Center, Chicago, IL 60612, United States 
Area:
Microbiology Biology
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"Alexander Mankin"
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Parents

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Harry F. Noller post-doc (PombeTree)

Children

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Aymen Yassin grad student 2006 University of Illinois at Chicago, Health Sciences Center
Marne J. Bailey grad student 2007 University of Illinois at Chicago, Health Sciences Center
Shalaka Samant grad student 2008 University of Illinois at Chicago, Health Sciences Center
Seok-Ming Toh grad student 2008 University of Illinois at Chicago, Health Sciences Center
Christopher A.J. Craddock post-doc University of Illinois, Chicago (Chemistry Tree)

Collaborators

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Jonathan D. Dinman collaborator 2016-2017 University of Chicago Medical Center (Cell Biology Tree)
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Publications

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Mangano K, Marks J, Klepacki D, et al. (2022) Context-based sensing of orthosomycin antibiotics by the translating ribosome. Nature Chemical Biology. 18: 1277-1286
Meydan S, Klepacki D, Karthikeyan S, et al. (2022) Response to: Lack of evidence for ribosomal frameshifting in ATP7B mRNA decoding. Molecular Cell
Tsai K, Stojković V, Lee DJ, et al. (2022) Structural basis for context-specific inhibition of translation by oxazolidinone antibiotics. Nature Structural & Molecular Biology. 29: 162-171
Zhang Y, Aleksashin NA, Klepacki D, et al. (2022) The context of the ribosome binding site in mRNAs defines specificity of action of kasugamycin, an inhibitor of translation initiation. Proceedings of the National Academy of Sciences of the United States of America. 119
Mitcheltree MJ, Pisipati A, Syroegin EA, et al. (2021) A synthetic antibiotic class overcoming bacterial multidrug resistance. Nature
Beckert B, Leroy EC, Sothiselvam S, et al. (2021) Structural and mechanistic basis for translation inhibition by macrolide and ketolide antibiotics. Nature Communications. 12: 4466
Svetlov MS, Koller TO, Meydan S, et al. (2021) Context-specific action of macrolide antibiotics on the eukaryotic ribosome. Nature Communications. 12: 2803
Svetlov MS, Syroegin EA, Aleksandrova EV, et al. (2021) Structure of Erm-modified 70S ribosome reveals the mechanism of macrolide resistance. Nature Chemical Biology
Svetlov MS, Cohen S, Alsuhebany N, et al. (2020) A long-distance rRNA base pair impacts the ability of macrolide antibiotics to kill bacteria. Proceedings of the National Academy of Sciences of the United States of America
Wade JT, Mankin A. (2020) Decision letter: Translational initiation in E. coli occurs at the correct sites genome-wide in the absence of mRNA-rRNA base-pairing Elife
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