Maria Radu, Ph.D.

Affiliations: 
2008 Microbiology and Immunology Temple University, Philadelphia, PA, United States 
Area:
Immunology, Cell Biology, Oncology
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"Maria Radu"

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Kenneth J. Soprano grad student 2008 Temple University
 (The role of p27 phosphorylation in mediating atRA sensitivity of ovarian carcinoma cells.)
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Publications

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Radu M, Chernoff J. (2017) Recent advances in methods to assess the activity of the kinome. F1000research. 6: 1004
Joseph GA, Lu M, Radu M, et al. (2016) Group I Paks promote skeletal myoblast differentiation in vivo and in vitro. Molecular and Cellular Biology
Reddy PN, Radu M, Xu K, et al. (2016) p21-activated kinase 2 regulates HSPC cytoskeleton, migration, and homing via CDC42 activation and interaction with β-Pix. Blood. 127: 1967-75
Radu M, Lyle K, Hoeflich KP, et al. (2015) p21-Activated Kinase 2 Regulates Endothelial Development and Function through the Bmk1/Erk5 Pathway. Molecular and Cellular Biology. 35: 3990-4005
Kosoff RE, Aslan JE, Kostyak JC, et al. (2015) Pak2 restrains endomitosis during megakaryopoiesis and alters cytoskeleton organization. Blood. 125: 2995-3005
Phee H, Au-Yeung BB, Pryshchep O, et al. (2014) Pak2 is required for actin cytoskeleton remodeling, TCR signaling, and normal thymocyte development and maturation. Elife. 3: e02270
Radu M, Semenova G, Kosoff R, et al. (2014) PAK signalling during the development and progression of cancer. Nature Reviews. Cancer. 14: 13-25
Phee H, Au-Yeung BB, Pryshchep O, et al. (2014) Author response: Pak2 is required for actin cytoskeleton remodeling, TCR signaling, and normal thymocyte development and maturation Elife
Radu M, Rawat SJ, Beeser A, et al. (2013) ArhGAP15, a Rac-specific GTPase-activating protein, plays a dual role in inhibiting small GTPase signaling. The Journal of Biological Chemistry. 288: 21117-25
Dorrance AM, De Vita S, Radu M, et al. (2013) The Rac GTPase effector p21-activated kinase is essential for hematopoietic stem/progenitor cell migration and engraftment. Blood. 121: 2474-82
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