Christopher J. Wilds, Ph.D.

Affiliations: 
2000 McGill University, Montreal, QC, Canada 
Area:
Organic Chemistry
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"Christopher Wilds"
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Masad J. Damha grad student 2000 McGill
 (Synthesis, physicochemical and biological properties of oligonucleotides containing 2-fluoro-2-deoxy-beta-D-arabinose.)
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Publications

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Pontarelli A, Wilds CJ. (2023) C5-Propynyl modified 2'-fluoroarabinonucleic acids form stable duplexes with RNA that are RNase H competent. Organic & Biomolecular Chemistry. 21: 7437-7446
Pontarelli A, Wilds CJ. (2023) Oligonucleotides Containing C5-Propynyl Modified Arabinonucleic Acids: Synthesis, Biophysical and Antisense Properties. Chembiochem : a European Journal of Chemical Biology. e202300068
Kozlov G, Mattijssen S, Jiang J, et al. (2022) Structural basis of 3'-end poly(A) RNA recognition by LARP1. Nucleic Acids Research
Pontarelli A, Liu JT, Movasat H, et al. (2022) Synthesis of a Convertible Linker Containing a Disulfide Group for Oligonucleotide Functionalization. Organic Letters
Pontarelli A, Wilds CJ. (2022) Arabinonucleic acids containing C5-propynyl modifications form stable hybrid duplexes with RNA that are efficiently degraded by E. coli RNase H. Bioorganic & Medicinal Chemistry Letters. 67: 128744
Copp W, Wilds CJ. (2020) O -Alkylguanine DNA Alkyltransferase Mediated Disassembly of a DNA Tetrahedron. Chemistry (Weinheim An Der Bergstrasse, Germany)
Behmand B, Noronha AM, Wilds CJ, et al. (2020) Hydrated electrons induce the formation of interstrand cross-links in DNA modified by cisplatin adducts. Journal of Radiation Research
Copp W, Wilds CJ. (2020) Frontispiece: O 6 ‐Alkylguanine DNA Alkyltransferase Mediated Disassembly of a DNA Tetrahedron Chemistry – a European Journal. 26
Sacre L, O'Flaherty DK, Archambault P, et al. (2017) O⁴-Alkylated-2'-deoxyuridine repair by O⁶-alkylguanine DNA alkyltransferase is augmented by a C5-fluorine modification. Chembiochem : a European Journal of Chemical Biology
Schoonhoven NM, O'Flaherty DK, McManus FP, et al. (2017) Altering Residue 134 Confers an Increased Substrate Range of Alkylated Nucleosides to the E. coli OGT Protein. Molecules (Basel, Switzerland). 22
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