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Karl O. Yu, Ph.D.

Affiliations: 
2007 Yeshiva University, New York, NY, United States 
Area:
Immunology, Cell Biology, Pharmaceutical Chemistry
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"Karl Yu"
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Steven A. Porcelli grad student 2007 Yeshiva University
 (An analysis of analogues of the alpha-galactosylceramide KRN7000 as activators of Valpha14-invariant NKT cells.)

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Publications

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Arora P, Baena A, Yu KO, et al. (2014) A single subset of dendritic cells controls the cytokine bias of natural killer T cell responses to diverse glycolipid antigens. Immunity. 40: 105-16
Yu KO, Porcelli SA, Shuman HA. (2013) In vitro derivation of macrophage from guinea pig bone marrow with human M-CSF. Journal of Immunological Methods. 389: 88-94
Yu ED, Girardi E, Wang J, et al. (2012) Structural basis for the recognition of C20:2-αGalCer by the invariant natural killer T cell receptor-like antibody L363. The Journal of Biological Chemistry. 287: 1269-78
Bricard G, Venkataswamy MM, Yu KO, et al. (2010) Α-galactosylceramide analogs with weak agonist activity for human iNKT cells define new candidate anti-inflammatory agents. Plos One. 5: e14374
Lombardi V, Stock P, Singh AK, et al. (2010) A CD1d-dependent antagonist inhibits the activation of invariant NKT cells and prevents development of allergen-induced airway hyperreactivity. Journal of Immunology (Baltimore, Md. : 1950). 184: 2107-15
Florence WC, Xia C, Gordy LE, et al. (2009) Adaptability of the semi-invariant natural killer T-cell receptor towards structurally diverse CD1d-restricted ligands. The Embo Journal. 28: 3781
Florence WC, Xia C, Gordy LE, et al. (2009) Adaptability of the semi-invariant natural killer T-cell receptor towards structurally diverse CD1d-restricted ligands. The Embo Journal. 28: 3579-90
Bai L, Sagiv Y, Liu Y, et al. (2009) Lysosomal recycling terminates CD1d-mediated presentation of short and polyunsaturated variants of the NKT cell lipid antigen alphaGalCer. Proceedings of the National Academy of Sciences of the United States of America. 106: 10254-9
Meyer-Bahlburg A, Andrews SF, Yu KO, et al. (2008) Characterization of a late transitional B cell population highly sensitive to BAFF-mediated homeostatic proliferation. The Journal of Experimental Medicine. 205: 155-68
Li Q, Ndonye RM, Illarionov PA, et al. (2007) Rapid identification of immunostimulatory alpha-galactosylceramides using synthetic combinatorial libraries. Journal of Combinatorial Chemistry. 9: 1084-93
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