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Dinuka M. De Silva, Ph.D.

Affiliations: 
2014 Pathology University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
Molecular Biology, Oncology
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"Dinuka De Silva"
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Parents

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Young E. Whang grad student 2014 UNC Chapel Hill
 (Role of androgen receptor co-repressor SLIRP in cell cycle regulation.)
Donald P Bottaro post-doc 2015-2019 National Cancer Institute (Chemistry Tree)

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Publications

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Felici A, Bottaro DP, Mangoni A, et al. (2022) Regression of Human Breast Carcinoma in Nude Mice after Ad Gene Therapy Is Mediated by Tumor Vascular Endothelial Cell Apoptosis. Cancers. 14
Lee YH, Lee MM, De Silva DM, et al. (2021) Autocrine signaling by receptor tyrosine kinases in urothelial carcinoma of the bladder. Plos One. 16: e0241766
Apolo AB, Nadal R, Tomita Y, et al. (2020) Cabozantinib in patients with platinum-refractory metastatic urothelial carcinoma: an open-label, single-centre, phase 2 trial. The Lancet. Oncology
De Silva D, Zhang Z, Liu Y, et al. (2019) Interaction between androgen receptor and coregulator SLIRP is regulated by Ack1 tyrosine kinase and androgen. Scientific Reports. 9: 18637
De Silva DM, Roy A, Kato T, et al. (2017) Targeting the hepatocyte growth factor/Met pathway in cancer. Biochemical Society Transactions
Matsumoto K, Umitsu M, De Silva DM, et al. (2017) HGF-MET in cancer progression and biomarker discovery. Cancer Science
Karaca M, Liu Y, Zhang Z, et al. (2015) Mutation of androgen receptor N-terminal phosphorylation site Tyr-267 leads to inhibition of nuclear translocation and DNA binding. Plos One. 10: e0126270
Chism DD, De Silva D, Whang YE. (2014) Mechanisms of acquired resistance to androgen receptor targeting drugs in castration-resistant prostate cancer. Expert Review of Anticancer Therapy. 14: 1369-78
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