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Gregory Thatcher

Affiliations: 
University of Illinois at Chicago, Chicago, IL, United States 
Area:
Biochemistry
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"Gregory Thatcher"
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Parents

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Ronald H. Kluger grad student University of Toronto

Children

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Isaac T Schiefer grad student
Ghenet K. Hagos grad student 2008 University of Illinois, Chicago
Samer Abdul-Hay grad student 2009 University of Illinois, Chicago
Irida Kastrati grad student 2009 University of Illinois, Chicago

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Publications

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Andreano KJ, Wardell SE, Baker JG, et al. (2020) G1T48, an oral selective estrogen receptor degrader, and the CDK4/6 inhibitor lerociclib inhibit tumor growth in animal models of endocrine-resistant breast cancer. Breast Cancer Research and Treatment
O'Regan R, Hurley R, Sachdev J, et al. (2020) Abstract P5-11-06: Phase 1 study of TTC-352 in patients with metastatic breast cancer progressing on endocrine therapy Cancer Research. 80
ORegan RM, Hurley R, Sachdev JC, et al. (2019) Abstract CT051: Phase I study of TTC-352 in patients with estrogen receptor-positive metastatic breast cancer Cancer Research. 79
Xiong R, Li Y, Zhao J, et al. (2019) Abstract 3830: Novel bromodomains and extra-terminal motif (BET) inhibitors developed against estrogen receptor positive, fulvestrant- and CDK4/6-resistant breast cancer models Cancer Research. 79: 3830-3830
Gaisina IN, Lee SH, Kaidery NA, et al. (2018) Activation of Nrf2 and Hypoxic Adaptive Response Contribute to Neuroprotection Elicited by Phenylhydroxamic Acid Selective HDAC6 Inhibitors. Acs Chemical Neuroscience
Petukhov PA, Abdelkarim H, Neelarapu R, et al. (2017) Design, Synthesis, Molecular Modeling, and Biological Evaluation of Novel Amine-based Histone Deacetylase Inhibitors. Chemmedchem
Kastrati I, Siklos MI, Brovkovych SD, et al. (2017) A Novel Strategy to Co-target Estrogen Receptor and Nuclear Factor κB Pathways with Hybrid Drugs for Breast Cancer Therapy. Hormones & Cancer
Kastrati I, Delgado-Rivera L, Georgieva G, et al. (2017) Synthesis and Characterization of an Aspirin-fumarate Prodrug that Inhibits NFκB Activity and Breast Cancer Stem Cells. Journal of Visualized Experiments : Jove
Pierce EN, Piyankarage SC, Dunlap TL, et al. (2016) Prodrugs Bioactivated to Quinones Target NF-κB and Multiple Protein Networks: Identification of the Quinonome. Chemical Research in Toxicology
Kastrati I, Siklos MI, Calderon-Gierszal EL, et al. (2016) Dimethyl Fumarate Inhibits the Nuclear Factor κB Pathway in Breast Cancer Cells by Covalent Modification of p65 Protein. The Journal of Biological Chemistry. 291: 3639-47
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