Joshua E. Allen, Ph.D.

Affiliations: 
2012 Biochemistry and Molecular Biophysics University of Pennsylvania, Philadelphia, PA, United States 
Area:
Oncology, Pharmacy
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"Joshua Allen"
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Wafik S. El-Deiry grad student 2012 Penn
 (Efficacy and mechanistic evaluation of TIC10, a novel antitumor agent.)
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Publications

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Paraghamian SE, Qiu J, Hawkins GM, et al. (2023) A novel dopamine receptor D2 antagonist (ONC206) potentiates the effects of olaparib in endometrial cancer. Cancer Biology & Therapy. 24: 2202104
Fan Y, Wang J, Fang Z, et al. (2022) Anti-Tumor and Anti-Invasive Effects of ONC201 on Ovarian Cancer Cells and a Transgenic Mouse Model of Serous Ovarian Cancer. Frontiers in Oncology. 12: 789450
Tucker K, Yin Y, Staley SA, et al. (2022) ONC206 has anti-tumorigenic effects in human ovarian cancer cells and in a transgenic mouse model of high-grade serous ovarian cancer. American Journal of Cancer Research. 12: 521-536
Anderson PM, Trucco MM, Tarapore RS, et al. (2022) Phase 2 Study of ONC201 in Neuroendocrine Tumors including Pheochromocytoma-Paraganglioma and Desmoplastic Small Round Cell Tumor. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research
Staley A, Tucker K, Yin Y, et al. (2021) Highly potent dopamine receptor D2 antagonist ONC206 demonstrates anti-tumorigenic activity in endometrial cancer. American Journal of Cancer Research. 11: 5374-5387
Mosquera MJ, Kim S, Bareja R, et al. (2021) Extracellular Matrix in Synthetic Hydrogel-based Prostate Cancer Organoids Regulate Therapeutic Response to EZH2 and DRD2 inhibitors. Advanced Materials (Deerfield Beach, Fla.). e2100096
Allen JE, Kline CLB, Prabhu VV, et al. (2021) Correction: Discovery and clinical introduction of first-in-class imipridone ONC201. Oncotarget. 12: 2231
He L, Bhat K, Ioannidis A, et al. (2021) Effects of the DRD2/3 Antagonist ONC201 and Radiation in Glioblastoma. Radiotherapy and Oncology : Journal of the European Society For Therapeutic Radiology and Oncology
Pierce SR, Fang Z, Yin Y, et al. (2021) Targeting dopamine receptor D2 as a novel therapeutic strategy in endometrial cancer. Journal of Experimental & Clinical Cancer Research : Cr. 40: 61
Bagheri-Yarmand R, Dadu R, Ye L, et al. (2021) ONC201 shows anti-cancer activity against medullary thyroid cancer via transcriptional inhibition of RET, VEGFR2, and IGFBP2. Molecular Cancer Therapeutics
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