Said Rahim, Ph.D.

Affiliations: 
2013 Biochemistry and Molecular Georgetown University, Washington, DC 
Area:
Biochemistry, Oncology, Molecular Biology
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"Said Rahim"
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Aykut Uren grad student 2013 Georgetown
 (Inhibiton of prostate cancer invasion by small molecule antagonists of ERG and ETV1 transcription factors.)
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Publications

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Çelik H, Sajwan KP, Selvanathan SP, et al. (2015) Ezrin Binds to DEAD-Box RNA Helicase DDX3 and Regulates Its Function and Protein Level. Molecular and Cellular Biology. 35: 3145-62
Simbulan-Rosenthal CM, Gaur A, Sanabria VA, et al. (2015) Inorganic polyphosphates are important for cell survival and motility of human skin keratinocytes. Experimental Dermatology
Celik H, Sajwan KP, Pai AV, et al. (2015) Abstract 3269: Ezrin binds to DEAD-box RNA helicase DDX3 and regulates its function and protein level Cancer Research. 75: 3269-3269
Rahim S, Minas T, Hong SH, et al. (2014) A small molecule inhibitor of ETV1, YK-4-279, prevents prostate cancer growth and metastasis in a mouse xenograft model. Plos One. 9: e114260
Tosso PN, Kong Y, Scher L, et al. (2014) Synthesis and structure-activity relationship studies of small molecule disruptors of EWS-FLI1 interactions in Ewing's sarcoma. Journal of Medicinal Chemistry. 57: 10290-303
Paige M, Kosturko G, Bulut G, et al. (2014) Design, synthesis and biological evaluation of ezrin inhibitors targeting metastatic osteosarcoma. Bioorganic & Medicinal Chemistry. 22: 478-87
Rahim S, Justvig S, Hong S, et al. (2014) Abstract 2949: YK-4-279 is a small molecule inhibitor of ETV1 and inhibits metastasis in a mouse model Cancer Research. 74: 2949-2949
Rahim S, Uren A. (2013) Emergence of ETS transcription factors as diagnostic tools and therapeutic targets in prostate cancer. American Journal of Translational Research. 5: 254-68
Rahim S, Justvig S, Hong S, et al. (2013) Abstract 5453: YK-4-279 inhibits ETS-positive prostate cancer cell metastasis in a mouse xenograft model. Cancer Research. 73: 5453-5453
Briggs JW, Ren L, Nguyen R, et al. (2012) The ezrin metastatic phenotype is associated with the initiation of protein translation. Neoplasia (New York, N.Y.). 14: 297-310
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