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Jonathan M. Backer

Affiliations: 
Yeshiva University, New York, NY, United States 
Area:
Cell Biology, Biochemistry
Website:
http://www.einstein.yu.edu/faculty/283/jonathan-backer/
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"Jonathan Backer"
Bio:

https://www.nature.com/articles/327341a0

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Parents

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Eliezar Aryeh Dawidowicz grad student 1987 Harvard Medical School
 (M.D. thesis: The reconstitution of a phospholipid flippase from rat liver endooplasmic [i.e. endoplasmic] reticulum.)
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Publications

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Salloum G, Bresnick AR, Backer JM. (2023) Macropinocytosis: mechanisms and regulation. The Biochemical Journal. 480: 335-362
Jakubik CT, Weckerly CC, Hammond GRV, et al. (2022) PIP abundance overcomes PI3K signaling selectivity in invadopodia. Febs Letters
Salloum G, Jakubik CT, Erami Z, et al. (2019) PI3Kβ is selectively required for growth factor-stimulated macropinocytosis. Journal of Cell Science
Erami Z, Heitz S, Bresnick AR, et al. (2019) PI3Kβ links integrin activation and PI(3,4)P production during invadopodial maturation. Molecular Biology of the Cell. mbcE19030182
Heitz SD, Hamelin DJ, Hoffmann RM, et al. (2019) A Single Discrete Rab5 Binding Site in PI3Kβ is Required for Tumor Cell Invasion. The Journal of Biological Chemistry
Bresnick AR, Backer JM. (2019) PI3Kβ - a versatile transducer for GPCR, RTK and small GTPase signaling. Endocrinology
Salloum G, Jakubik C, Bresnick AR, et al. (2019) Abstract 3431: PI3Kbeta regulates macropinocytosis in PTEN-null tumor cells Cancer Research
Norwood Toro LE, Wang Y, Condeelis JS, et al. (2018) Myosin-IIA Heavy Chain Phosphorylation on S1943 Regulates Tumor Metastasis. Experimental Cell Research
Erami Z, Bresnick AR, Backer JM. (2018) Abstract 3165: PI 3-kinase-beta regulates invadopodia maturation and beta-1 integrin signaling Cancer Research. 78: 3165-3165
Dulyaninova NG, Ruiz PD, Gamble MJ, et al. (2017) S100A4 Regulates Macrophage Invasion by Distinct Myosin-Dependent and Independent Mechanisms. Molecular Biology of the Cell
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