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Vickie Tsui, Ph.D.

Affiliations: 
2001 Scripps Research Institute, La Jolla, La Jolla, CA, United States 
Area:
Biochemistry, General Biophysics
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"Vickie Tsui"
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David A. Case grad student 2001 Scripps Institute
 (NMR restraints and solvent models in molecular dynamics simulations: Effects on biomolecular structure and intermolecular interactions.)

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Taylor AM, Bailey C, Belmont LD, et al. (2022) GNE-064: A Potent, Selective, and Orally Bioavailable Chemical Probe for the Bromodomains of SMARCA2 and SMARCA4 and the Fifth Bromodomain of PBRM1. Journal of Medicinal Chemistry
Nittinger E, Gibbons P, Eigenbrot C, et al. (2019) Water molecules in protein-ligand interfaces. Evaluation of software tools and SAR comparison. Journal of Computer-Aided Molecular Design
Wang X, Blackaby WP, Allen V, et al. (2019) Optimization of Pan-Pim Kinase Activity and Oral Bioavailability Leading to Diaminopyrazole (GDC-0339) for the Treatment of Multiple Myeloma. Journal of Medicinal Chemistry
Wang S, Tsui V, Crawford TD, et al. (2018) GNE-371, a Potent and Selective Chemical Probe for the Second Bromodomains of Human Transcription-Initiation-Factor TFIID Subunit 1 and Transcription-Initiation-Factor TFIID Subunit 1-like. Journal of Medicinal Chemistry
Wertz I, Kategaya L, Lello PD, et al. (2018) Abstract SY23-03: Development and mechanistic characterization of USP7 deubiquitinase inhibitors Cancer Research. 78
Lai KW, Romero FA, Tsui V, et al. (2017) Design and synthesis of a biaryl series as inhibitors for the bromodomains of CBP/P300. Bioorganic & Medicinal Chemistry Letters
Di Lello P, Pastor R, Murray JM, et al. (2017) Discovery of Small-Molecule Inhibitors of Ubiquitin Specific Protease 7 (USP7) Using Integrated NMR and In-Silico Techniques. Journal of Medicinal Chemistry
Bronner SM, Murray JM, Romero FA, et al. (2017) A Unique Approach to Design Potent and Selective Cyclic Adenosine Monophosphate Response Element Binding Protein, Binding Protein (CBP) Inhibitors. Journal of Medicinal Chemistry
Kategaya L, Di Lello P, Rougé L, et al. (2017) USP7 small-molecule inhibitors interfere with ubiquitin binding. Nature
Romero FA, Murray JM, Lai KW, et al. (2017) GNE-781, A Highly Advanced Potent and Selective Bromodomain Inhibitor of Cyclic Adenosine Monophosphate Response Element Binding Protein, Binding Protein (CBP). Journal of Medicinal Chemistry
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