Ermira Pazolli, Ph.D.

Affiliations: 
2010 Biology & Biomedical Sciences (Molecular Cell Biology) Washington University, Saint Louis, St. Louis, MO 
Area:
Cell Biology
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"Ermira Pazolli"

Parents

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Sheila A. Stewart grad student 2010 Washington University
 (The function and regulation of senescent stromal-derived OPN.)
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Publications

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Aird D, Teng T, Huang CL, et al. (2019) Sensitivity to splicing modulation of BCL2 family genes defines cancer therapeutic strategies for splicing modulators. Nature Communications. 10: 137
Aird D, Teng T, Huang C, et al. (2019) Abstract 281: Sensitivity to splicing modulation of BCL2 family genes reveals cancer therapeutic strategies for splicing modulators Cancer Research. 79: 281-281
Seiler M, Yoshimi A, Darman R, et al. (2018) H3B-8800, an orally available small-molecule splicing modulator, induces lethality in spliceosome-mutant cancers. Nature Medicine
Flanagan KC, Alspach E, Pazolli E, et al. (2018) c-Myb and C/EBPβ regulate OPN and other senescence-associated secretory phenotype factors. Oncotarget. 9: 21-36
Buonamici S, Yoshimi A, Thomas M, et al. (2017) Abstract 1185: H3B-8800, a novel orally available SF3b modulator, shows preclinical efficacy across spliceosome mutant cancers Cancer Research. 77: 1185-1185
Weir HM, Bradbury RH, Lawson M, et al. (2016) AZD9496: An oral estrogen receptor inhibitor that blocks the growth of ER-positive and ESR1 mutant breast tumours in preclinical models. Cancer Research
Buonamici S, Yoshimi A, Thomas M, et al. (2016) H3B-8800, an Orally Bioavailable Modulator of the SF3b Complex, Shows Efficacy in Spliceosome-Mutant Myeloid Malignancies Blood. 128: 966-966
Buonamici S, Darman R, Perino S, et al. (2015) Heterozygous Hotspot SF3B1 Mutations Found in Myelodysplastic Syndromes Downregulate Genes Involved in Differentiation of Erythroid Cells Blood. 126: 1643-1643
Park ES, Aicher M, Aird D, et al. (2015) Abstract 2941: Targeting MCL1-dependent cancers through RNA splicing modulation Cancer Research. 75: 2941-2941
Aird D, Pazolli E, Furman C, et al. (2015) Abstract C8: Targeting MCL1-dependent cancers with SF3B splicing modulators Molecular Cancer Therapeutics. 14
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