Philip N. Tsichlis

Affiliations: 
Biochemistry Sackler School of Graduate Biomedical Sciences (Tufts University) 
Area:
Biochemistry
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"Philip Tsichlis"
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Laliotis GI, Kenney AD, Chavdoula E, et al. (2021) Phosphor-IWS1-dependent U2AF2 splicing regulates trafficking of CAR-E-positive intronless gene mRNAs and sensitivity to viral infection. Communications Biology. 4: 1179
Laliotis GI, Chavdoula E, Paraskevopoulou MD, et al. (2021) AKT3-mediated IWS1 phosphorylation promotes the proliferation of EGFR-mutant lung adenocarcinomas through cell cycle-regulated U2AF2 RNA splicing. Nature Communications. 12: 4624
Polytarchou C, Hatziapostolou M, Yau TO, et al. (2020) Akt3 induces oxidative stress and DNA damage by activating the NADPH oxidase via phosphorylation of p47. Proceedings of the National Academy of Sciences of the United States of America
Deiktakis EE, Abrams M, Tsapara A, et al. (2020) Identification of Structural Elements of the Lysine Specific Demethylase 2B CxxC Domain Associated with Replicative Senescence Bypass in Primary Mouse Cells. The Protein Journal
Orlacchio A, Stark AE, Foray C, et al. (2018) Genetic ablation of interacting with Spt6 (Iws1) causes early embryonic lethality. Plos One. 13: e0201030
Zacharopoulou N, Tsapara A, Kallergi G, et al. (2018) The Epigenetic Factor KDM2B Regulates EMT and Small GTPases in Colon Tumor Cells. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 47: 368-377
Zacharopoulou N, Tsapara A, Kallergi G, et al. (2018) The epigenetic factor KDM2B regulates cell adhesion, small rho GTPases, actin cytoskeleton and migration in prostate cancer cells. Biochimica Et Biophysica Acta. 1865: 587-597
Roper J, Tammela T, Cetinbas NM, et al. (2018) Abstract B38: In vivo genome editing and organoid transplantation models of colorectal cancer and metastasis Cancer Research. 78
McRee SK, Pietruska JR, Tsichlis PN, et al. (2018) Abstract 1112: AKT2 loss impairs BRAF mutant melanoma metastasis Cancer Research. 78: 1112-1112
Peterson JN, Lin B, Shin J, et al. (2017) THE REPLICATION OF JCV DNA IN THE G144 OLIGODENDROCYTE CELL LINE IS DEPENDENT UPON AKT. Journal of Virology
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