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Adam D. Pierce, Ph.D.

Affiliations: 
2011 Molecular Medicine University of Maryland School of Medicine, Baltimore, MD, United States 
Area:
Molecular Biology
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Antonino Passaniti grad student 2011 University of Maryland Medical School
 (Regulation of glucose-activated RUNX2 phosphorylation: Effects on endothelial cell proliferation and an angiogenic phenotype.)

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Melville Z, Hernandez-Ochoa EO, Pratt SJ, et al. (2017) The activation of PKA by the calcium-binding protein S100A1 is independent of cyclic AMP. Biochemistry
Alasady MJ, Adipietro KA, Pierce AD, et al. (2017) Abstract 315: S100B regulates IL-6 signaling via the p90 ribosomal S6 kinase (RSK) in malignant melanoma Cancer Research. 77: 315-315
Cavalier MC, Melville Z, Aligholizadeh E, et al. (2016) Novel protein-inhibitor interactions in site 3 of Ca(2+)-bound S100B as discovered by X-ray crystallography. Acta Crystallographica. Section D, Structural Biology. 72: 753-760
Mochin MT, Underwood KF, Cooper B, et al. (2015) Hyperglycemia and redox status regulate RUNX2 DNA-binding and an angiogenic phenotype in endothelial cells. Microvascular Research. 97: 55-64
Mochin MT, Underwood KF, Cooper B, et al. (2015) Hyperglycemia and redox status regulate RUNX2 DNA-binding and an angiogenic phenotype in endothelial cells Microvascular Research. 97: 55-64
Cavalier MC, Pierce AD, Wilder PT, et al. (2014) Covalent small molecule inhibitors of Ca(2+)-bound S100B. Biochemistry. 53: 6628-40
Hartman KG, Vitolo MI, Pierce AD, et al. (2014) Complex formation between S100B protein and the p90 ribosomal S6 kinase (RSK) in malignant melanoma is calcium-dependent and inhibits extracellular signal-regulated kinase (ERK)-mediated phosphorylation of RSK. The Journal of Biological Chemistry. 289: 12886-95
Pierce AD. (2014) Abstract 4201: Activation of p90 ribosomal S6 kinase (RSK) and downstream targets are directly regulated by S100B protein in malignant melanoma Cancer Research. 74: 4201-4201
Pierce AD, Hartman KG, Weber D. (2013) Abstract 5243: The novel calcium-dependent direct binding of S100B to p90 ribosomal S6 kinase (RSK) decreases MAP kinase-mediated RSK activation in malignant melanoma. Cancer Research. 73: 5243-5243
Underwood KF, D'Souza DR, Mochin-Peters M, et al. (2012) Regulation of RUNX2 transcription factor-DNA interactions and cell proliferation by vitamin D3 (cholecalciferol) prohormone activity. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 27: 913-25
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