Louis R. Ghanem, Ph.D.

Affiliations: 
2005 University of Pittsburgh, Pittsburgh, PA, United States 
Area:
Molecular Biology
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Richard Steinman grad student 2005 University of Pittsburgh
 (The role and regulation of p21(WAF1/CIP1) in myelopoiesis.)
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Publications

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Ernst J, Ghanem L, Bar-Joseph Z, et al. (2009) IL-3 and oncogenic Abl regulate the myeloblast transcriptome by altering mRNA stability. Plos One. 4: e7469
Ernst J, Bar-Joseph Z, Ghanem L, et al. (2008) IL-3 Coordination of the Myeloblast Transcriptome by Modulating mRNA Stability Blood. 112: 3863-3863
Duensing A, Ghanem L, Steinman RA, et al. (2006) p21(Waf1/Cip1) deficiency stimulates centriole overduplication. Cell Cycle (Georgetown, Tex.). 5: 2899-902
Ghanem L, Steinman RA. (2006) p21Waf1 inhibits granulocytic differentiation of 32Dcl3 cells. Leukemia Research. 30: 1285-92
Ghanem L, Steinman R. (2005) A proapoptotic function of p21 in differentiating granulocytes. Leukemia Research. 29: 1315-23
Ghanem L, Steinman RA. (2005) IL-3 Inhibits Terminal Granulocytic Differentiation by Inducing the Binding of Stabilizing Proteins to a 300 Base Pair Region within p21cip1/waf1 Messenger RNA. Blood. 106: 3152-3152
Ghanem L, Steinman RA. (2004) P21 Induces Apoptosis in 32d Cells Undergoing G-Csf-Stimulated Differentiation--This Effect Requires Threonine 57 in Its Cdk2-Inhibitory Domain. Blood. 104: 1273-1273
Pandey P, Avraham S, Kumar S, et al. (1999) Activation of p38 mitogen-activated protein kinase by PYK2/related adhesion focal tyrosine kinase-dependent mechanism. The Journal of Biological Chemistry. 274: 10140-4
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