Arelis Salas, Ph.D.

Affiliations: 
2010 Medical University of South Carolina, Charleston, SC, United States 
Area:
Molecular Biology
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"Arelis Salas"
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Besim Ogretmen grad student 2010 MUSC
 (Regulation of imatinib-resistance through Ber-Abl stability by SK1/S1P/S1PR signaling in chronic myeloid leukemia (CML).)
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Publications

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Salas A, Ponnusamy S, Senkal CE, et al. (2011) Sphingosine kinase-1 and sphingosine 1-phosphate receptor 2 mediate Bcr-Abl1 stability and drug resistance by modulation of protein phosphatase 2A. Blood. 117: 5941-52
Ponnusamy S, Meyers-Needham M, Senkal CE, et al. (2010) Sphingolipids and cancer: ceramide and sphingosine-1-phosphate in the regulation of cell death and drug resistance. Future Oncology (London, England). 6: 1603-24
Baran Y, Salas A, Senkal CE, et al. (2007) Alterations of ceramide/sphingosine 1-phosphate rheostat involved in the regulation of resistance to imatinib-induced apoptosis in K562 human chronic myeloid leukemia cells. The Journal of Biological Chemistry. 282: 10922-34
Sundararaj KP, Wood RE, Ponnusamy S, et al. (2004) Rapid shortening of telomere length in response to ceramide involves the inhibition of telomere binding activity of nuclear glyceraldehyde-3-phosphate dehydrogenase. The Journal of Biological Chemistry. 279: 6152-62
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