Edwin W. Lai, Ph.D.

Affiliations: 
2009 Tumor Biology Georgetown University, Washington, DC 
Area:
Oncology, Cell Biology, Animal Physiology Biology
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Chris Albanese grad student 2009 Georgetown
 (Molecular characterization of animal models of pheochromocytoma.)
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Publications

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Stauffer JK, Orentas RJ, Lincoln E, et al. (2012) High-throughput molecular and histopathologic profiling of tumor tissue in a novel transplantable model of murine neuroblastoma: new tools for pediatric drug discovery. Cancer Investigation. 30: 343-63
He J, Makey D, Fojo T, et al. (2009) Successful chemotherapy of hepatic metastases in a case of succinate dehydrogenase subunit B-related paraganglioma. Endocrine. 36: 189-93
Lai EW, Joshi BH, Martiniova L, et al. (2009) Overexpression of interleukin-13 receptor-alpha2 in neuroendocrine malignant pheochromocytoma: a novel target for receptor directed anti-cancer therapy. The Journal of Clinical Endocrinology and Metabolism. 94: 2952-7
Rodriguez OC, Lai EW, Vissapragada S, et al. (2009) A reduction in Pten tumor suppressor activity promotes ErbB-2-induced mouse prostate adenocarcinoma formation through the activation of signaling cascades downstream of PDK1. The American Journal of Pathology. 174: 2051-60
Martiniova L, Lai EW, Elkahloun AG, et al. (2009) Characterization of an animal model of aggressive metastatic pheochromocytoma linked to a specific gene signature. Clinical & Experimental Metastasis. 26: 239-50
Ohta S, Lai EW, Morris JC, et al. (2008) Metastasis-associated gene expression profile of liver and subcutaneous lesions derived from mouse pheochromocytoma cells. Molecular Carcinogenesis. 47: 245-51
Lai EW, Rodriguez OC, Aventian M, et al. (2007) ErbB-2 induces bilateral adrenal pheochromocytoma formation in mice. Cell Cycle (Georgetown, Tex.). 6: 1946-50
Alesci S, Perera SM, Lai EW, et al. (2007) Adenoviral gene transfer in bovine adrenomedullary and murine pheochromocytoma cells: potential clinical and therapeutic relevance. Endocrinology. 148: 3900-7
Martiniova L, Ohta S, Guion P, et al. (2006) Anatomical and functional imaging of tumors in animal models: focus on pheochromocytoma. Annals of the New York Academy of Sciences. 1073: 392-404
Ohta S, Lai EW, Morris JC, et al. (2006) MicroCT for high-resolution imaging of ectopic pheochromocytoma tumors in the liver of nude mice. International Journal of Cancer. 119: 2236-41
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