Sandra Aung, Ph.D.

Affiliations: 
2000 Vanderbilt University, Nashville, TN 
Area:
Immunology
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"Sandra Aung"

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Barney S. Graham grad student 2000 Vanderbilt
 (Molecular mechanisms of CD8(+) T lymphocyte-induced cytotoxicity, interleukin-4, and respiratory syncytial virus pathogenesis.)
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Publications

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Diab A, Tannir NM, Bentebibel SE, et al. (2020) Bempegaldesleukin (NKTR-214) plus Nivolumab in Patients with Advanced Solid Tumors: Phase I Dose-Escalation Study of Safety, Efficacy, and Immune Activation (PIVOT-02). Cancer Discovery
Bentebibel SE, Hurwitz ME, Bernatchez C, et al. (2019) A First-in-Human Study and Biomarker Analysis of NKTR-214, a Novel IL-2-Receptor Beta/Gamma (βγ)-Biased Cytokine, in Patients With Advanced or Metastatic Solid Tumors. Cancer Discovery
van de Ven R, Hilton TL, Hu HM, et al. (2018) Autophagosome-based strategy to monitor apparent tumor-specific CD8 T cells in patients with prostate cancer. Oncoimmunology. 7: e1466766
Vaena DA, Chaves J, Vogelzang NJ, et al. (2018) PROPEL: A phase 1/2 trial of NKTR-214 (CD122-biased agonist) combined with anti-PD-1 (pembrolizumab) or anti-PD-L1 (atezolizumab) in patients (pts) with advanced solid tumors. Journal of Clinical Oncology. 36: TPS3115-TPS3115
Sanborn RE, Ross HJ, Aung S, et al. (2017) A pilot study of an autologous tumor-derived autophagosome vaccine with docetaxel in patients with stage IV non-small cell lung cancer. Journal For Immunotherapy of Cancer. 5: 103
Hurwitz ME, Diab A, Bernatchez C, et al. (2017) Effect of NKTR-214 on the number and activity of CD8+ tumor infiltrating lymphocytes in patients with advanced renal cell carcinoma. Journal of Clinical Oncology. 35: 454-454
Diab A, Tannir NM, Bernatchez C, et al. (2017) A phase 1/2 study of a novel IL-2 cytokine, NKTR-214, and nivolumab in patients with select locally advanced or metastatic solid tumors. Journal of Clinical Oncology. 35: e14040-e14040
Bernatchez C, Haymaker CL, Hurwitz ME, et al. (2017) Effect of a novel IL-2 cytokine immune agonist (NKTR-214) on proliferating CD8+T cells and PD-1 expression on immune cells in the tumor microenvironment in patients with prior checkpoint therapy. Journal of Clinical Oncology. 35: 2545-2545
Buchbinder EI, Gunturi A, Perritt J, et al. (2016) A retrospective analysis of High-Dose Interleukin-2 (HD IL-2) following Ipilimumab in metastatic melanoma. Journal For Immunotherapy of Cancer. 4: 52
Clark J, Wong M, Daniels G, et al. (2015) Stable disease after high dose interleukin-2 (HD IL-2) immunotherapy: observations on long term survival and clinical benefit of additional HD IL-2 F1000research. 6
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