Reena Shakya, Ph.D.

Affiliations: 
2005 Columbia University, New York, NY 
Area:
Genetics, Molecular Biology
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"Reena Shakya"

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Frank Costantini grad student 2005 Columbia
 (The role of GDNF /Ret and FGF7/FGFR2IIIb signaling in the development of the excretory system.)
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Publications

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Dauch C, Shim S, Cole MW, et al. (2022) loss drives aggressive tumor phenotypes in cutaneous squamous cell carcinoma. American Journal of Cancer Research. 12: 1309-1322
Purde V, Kudryashova E, Heisler DB, et al. (2020) Intein-mediated cytoplasmic reconstitution of a split toxin enables selective cell ablation in mixed populations and tumor xenografts. Proceedings of the National Academy of Sciences of the United States of America
Park D, Bergin SM, Jones D, et al. (2020) Ablation of the Brca1-Palb2 interaction phenocopies Fanconi anemia in mice. Cancer Research
Choueiry F, Torok M, Shakya R, et al. (2020) CD200 promotes immunosuppression in the pancreatic tumor microenvironment. Journal For Immunotherapy of Cancer. 8
Geisler JA, Spehar JM, Steck SA, et al. (2020) Modeling Brain Metastases Through Intracranial Injection and Magnetic Resonance Imaging. Journal of Visualized Experiments : Jove
Park D, Shakya R, Koivisto C, et al. (2019) Murine models for familial pancreatic cancer: Histopathology, latency and drug sensitivity among cancers of Palb2, Brca1 and Brca2 mutant mouse strains. Plos One. 14: e0226714
Seligson ND, Stets CW, Demoret BW, et al. (2019) Inhibition of histone deacetylase 2 reduces MDM2 expression and reduces tumor growth in dedifferentiated liposarcoma. Oncotarget. 10: 5671-5679
Ware MB, McQuinn C, Mace TA, et al. (2019) Abstract B59: IL-6 regulates CTLA4 expression on CD4+ T-cells and dual antibody blockade of IL-6 and CTLA4 leads to tumor regression in an orthotopic murine model of pancreatic ductal adenocarcinoma Cancer Research. 79
Spaeth-Cook D, Burch M, Belton R, et al. (2018) Loss of TXNIP enhances peritoneal metastasis and can be abrogated by dual TORC1/2 inhibition. Oncotarget. 9: 35676-35686
Farren MR, Hennessey RC, Shakya R, et al. (2017) The exportin-1 inhibitor selinexor exerts superior anti-tumor activity when combined with T cell checkpoint inhibitors. Molecular Cancer Therapeutics
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